Chapman E - Search Results

1

Unfolded DapA forms aggregates when diluted into free solution, confounding comparison with folding by the GroEL/GroES chaperonin system.

Ambrose A, Fenton W, Mason DJ, Chapman E, Horwich AL. Ambrose A, et al. Among authors: chapman e. FEBS Lett. 2015 Feb 13;589(4):497-499. doi: 10.1016/j.febslet.2015.01.008. Epub 2015 Jan 17. FEBS Lett. 2015. PMID: 25601566 Free PMC article.

2

Putting the case for the nurse. Handling and avoiding clinical negligence claims.

Chapman EJ, Mason D. Chapman EJ, et al. Prof Nurse. 1994 Apr;9(7):443-4, 446-7. Prof Nurse. 1994. PMID: 8177897

3

Global aggregation of newly translated proteins in an Escherichia coli strain deficient of the chaperonin GroEL.

Chapman E, Farr GW, Usaite R, Furtak K, Fenton WA, Chaudhuri TK, Hondorp ER, Matthews RG, Wolf SG, Yates JR, Pypaert M, Horwich AL. Chapman E, et al. Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):15800-5. doi: 10.1073/pnas.0607534103. Epub 2006 Oct 16. Proc Natl Acad Sci U S A. 2006. PMID: 17043235 Free PMC article.

4

Two families of chaperonin: physiology and mechanism.

Horwich AL, Fenton WA, Chapman E, Farr GW. Horwich AL, et al. Among authors: chapman e. Annu Rev Cell Dev Biol. 2007;23:115-45. doi: 10.1146/annurev.cellbio.23.090506.123555. Annu Rev Cell Dev Biol. 2007. PMID: 17489689 Review.

5

Requirement for binding multiple ATPs to convert a GroEL ring to the folding-active state.

Chapman E, Farr GW, Fenton WA, Johnson SM, Horwich AL. Chapman E, et al. Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19205-10. doi: 10.1073/pnas.0810657105. Epub 2008 Dec 2. Proc Natl Acad Sci U S A. 2008. PMID: 19050077 Free PMC article.

6

A small molecule inhibitor selective for a variant ATP-binding site of the chaperonin GroEL.

Chapman E, Farr GW, Furtak K, Horwich AL. Chapman E, et al. Bioorg Med Chem Lett. 2009 Feb 1;19(3):811-3. doi: 10.1016/j.bmcl.2008.12.015. Epub 2008 Dec 7. Bioorg Med Chem Lett. 2009. PMID: 19110421 Free PMC article.

7

Localization of GroEL determined by in vivo incorporation of a fluorescent amino acid.

Charbon G, Wang J, Brustad E, Schultz PG, Horwich AL, Jacobs-Wagner C, Chapman E. Charbon G, et al. Among authors: chapman e. Bioorg Med Chem Lett. 2011 Oct 15;21(20):6067-70. doi: 10.1016/j.bmcl.2011.08.057. Epub 2011 Aug 19. Bioorg Med Chem Lett. 2011. PMID: 21890355 Free PMC article.

8

A biochemical screen for GroEL/GroES inhibitors.

Johnson SM, Sharif O, Mak PA, Wang HT, Engels IH, Brinker A, Schultz PG, Horwich AL, Chapman E. Johnson SM, et al. Among authors: chapman e. Bioorg Med Chem Lett. 2014 Feb 1;24(3):786-9. doi: 10.1016/j.bmcl.2013.12.100. Epub 2014 Jan 2. Bioorg Med Chem Lett. 2014. PMID: 24418775

9

Functional chromatography reveals three natural products that target the same protein with distinct mechanisms of action.

Kang MJ, Wu T, Wijeratne EM, Lau EC, Mason DJ, Mesa C, Tillotson J, Zhang DD, Gunatilaka AA, La Clair JJ, Chapman E. Kang MJ, et al. Among authors: chapman e. Chembiochem. 2014 Sep 22;15(14):2125-31. doi: 10.1002/cbic.201402258. Epub 2014 Aug 14. Chembiochem. 2014. PMID: 25125376 Free PMC article.

10

Functional chromatographic technique for natural product isolation.

Lau EC, Mason DJ, Eichhorst N, Engelder P, Mesa C, Kithsiri Wijeratne EM, Gunaherath GM, Gunatilaka AA, La Clair JJ, Chapman E. Lau EC, et al. Among authors: chapman e. Org Biomol Chem. 2015 Feb 28;13(8):2255-9. doi: 10.1039/c4ob02292k. Org Biomol Chem. 2015. PMID: 25588099 Free PMC article.

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