Kostikov A - Search Results

1

In vivo characterization of metabotropic glutamate receptor type 5 abnormalities in behavioral variant FTD.

Leuzy A, Zimmer ER, Dubois J, Pruessner J, Cooperman C, Soucy JP, Kostikov A, Schirmaccher E, Désautels R, Gauthier S, Rosa-Neto P. Leuzy A, et al. Among authors: kostikov a. Brain Struct Funct. 2016 Apr;221(3):1387-402. doi: 10.1007/s00429-014-0978-3. Epub 2015 Jan 18. Brain Struct Funct. 2016. PMID: 25596865

2

PET imaging of cholinergic deficits in rats using [18F]fluoroethoxybenzovesamicol ([18F]FEOBV).

Parent M, Bedard MA, Aliaga A, Soucy JP, Landry St-Pierre E, Cyr M, Kostikov A, Schirrmacher E, Massarweh G, Rosa-Neto P. Parent M, et al. Among authors: kostikov a. Neuroimage. 2012 Aug 1;62(1):555-61. doi: 10.1016/j.neuroimage.2012.04.032. Epub 2012 Apr 25. Neuroimage. 2012. PMID: 22555071

3

Concordance between in vivo and postmortem measurements of cholinergic denervation in rats using PET with [18F]FEOBV and choline acetyltransferase immunochemistry.

Parent MJ, Cyr M, Aliaga A, Kostikov A, Schirrmacher E, Soucy JP, Mechawar N, Rosa-Neto P, Bedard MA. Parent MJ, et al. Among authors: kostikov a. EJNMMI Res. 2013 Oct 9;3(1):70. doi: 10.1186/2191-219X-3-70. EJNMMI Res. 2013. PMID: 24103360 Free PMC article.

4

PET imaging with [¹⁸F]fluoroethoxybenzovesamicol ([¹⁸F]FEOBV) following selective lesion of cholinergic pedunculopontine tegmental neurons in rat.

Cyr M, Parent MJ, Mechawar N, Rosa-Neto P, Soucy JP, Aliaga A, Kostikov A, Maclaren DA, Clark SD, Bedard MA. Cyr M, et al. Among authors: kostikov a. Nucl Med Biol. 2014 Jan;41(1):96-101. doi: 10.1016/j.nucmedbio.2013.10.004. Epub 2013 Oct 21. Nucl Med Biol. 2014. PMID: 24267056

5

Cholinergic Depletion in Alzheimer's Disease Shown by [ (18) F]FEOBV Autoradiography.

Parent MJ, Bedard MA, Aliaga A, Minuzzi L, Mechawar N, Soucy JP, Schirrmacher E, Kostikov A, Gauthier SG, Rosa-Neto P. Parent MJ, et al. Among authors: kostikov a. Int J Mol Imaging. 2013;2013:205045. doi: 10.1155/2013/205045. Epub 2013 Nov 10. Int J Mol Imaging. 2013. PMID: 24324884 Free PMC article.

6

Syntheses and evaluation of carbon-11- and fluorine-18-radiolabeled pan-tropomyosin receptor kinase (Trk) inhibitors: exploration of the 4-aza-2-oxindole scaffold as Trk PET imaging agents.

Bernard-Gauthier V, Aliaga A, Aliaga A, Boudjemeline M, Hopewell R, Kostikov A, Rosa-Neto P, Thiel A, Schirrmacher R. Bernard-Gauthier V, et al. Among authors: kostikov a. ACS Chem Neurosci. 2015 Feb 18;6(2):260-76. doi: 10.1021/cn500193f. Epub 2014 Nov 10. ACS Chem Neurosci. 2015. PMID: 25350780

7

In Vivo Evaluation of ¹⁸F-SiFAlin-Modified TATE: A Potential Challenge for ⁶⁸Ga-DOTATATE, the Clinical Gold Standard for Somatostatin Receptor Imaging with PET.

Niedermoser S, Chin J, Wängler C, Kostikov A, Bernard-Gauthier V, Vogler N, Soucy JP, McEwan AJ, Schirrmacher R, Wängler B. Niedermoser S, et al. Among authors: kostikov a. J Nucl Med. 2015 Jul;56(7):1100-5. doi: 10.2967/jnumed.114.149583. Epub 2015 May 14. J Nucl Med. 2015. PMID: 25977461 Free article.

8

Towards the PET radiotracer for p75 neurotrophin receptor: [(11)C]LM11A-24 shows biological activity in vitro, but unfavorable ex vivo and in vivo profile.

Gibon J, Kang MS, Aliaga A, Sharif B, Rosa-Neto P, Séguéla P, Barker PA, Kostikov A. Gibon J, et al. Among authors: kostikov a. Bioorg Med Chem. 2016 Oct 1;24(19):4759-4765. doi: 10.1016/j.bmc.2016.08.020. Epub 2016 Aug 13. Bioorg Med Chem. 2016. PMID: 27567078

9

Development of "[¹¹C]kits" for a fast, efficient and reliable production of carbon-11 labeled radiopharmaceuticals for Positron Emission Tomography.

Jolly D, Hopewell R, Kovacevic M, Li QY, Soucy JP, Kostikov A. Jolly D, et al. Among authors: kostikov a. Appl Radiat Isot. 2017 Mar;121:76-81. doi: 10.1016/j.apradiso.2016.11.020. Epub 2016 Dec 2. Appl Radiat Isot. 2017. PMID: 28038410

10

A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation, and First-in-Human.

Bernard-Gauthier V, Bailey JJ, Mossine AV, Lindner S, Vomacka L, Aliaga A, Shao X, Quesada CA, Sherman P, Mahringer A, Kostikov A, Grand'Maison M, Rosa-Neto P, Soucy JP, Thiel A, Kaplan DR, Fricker G, Wängler B, Bartenstein P, Schirrmacher R, Scott PJH. Bernard-Gauthier V, et al. Among authors: kostikov a. J Med Chem. 2017 Aug 24;60(16):6897-6910. doi: 10.1021/acs.jmedchem.7b00396. Epub 2017 Jul 21. J Med Chem. 2017. PMID: 28696690

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