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A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma.
Sharma A, Menche J, Huang CC, Ort T, Zhou X, Kitsak M, Sahni N, Thibault D, Voung L, Guo F, Ghiassian SD, Gulbahce N, Baribaud F, Tocker J, Dobrin R, Barnathan E, Liu H, Panettieri RA Jr, Tantisira KG, Qiu W, Raby BA, Silverman EK, Vidal M, Weiss ST, Barabási AL. Sharma A, et al. Among authors: barabasi al. Hum Mol Genet. 2015 Jun 1;24(11):3005-20. doi: 10.1093/hmg/ddv001. Epub 2015 Jan 12. Hum Mol Genet. 2015. PMID: 25586491 Free PMC article.
The human disease network.
Goh KI, Cusick ME, Valle D, Childs B, Vidal M, Barabási AL. Goh KI, et al. Among authors: barabasi al. Proc Natl Acad Sci U S A. 2007 May 22;104(21):8685-90. doi: 10.1073/pnas.0701361104. Epub 2007 May 14. Proc Natl Acad Sci U S A. 2007. PMID: 17502601 Free PMC article.
Drug-target network.
Yildirim MA, Goh KI, Cusick ME, Barabási AL, Vidal M. Yildirim MA, et al. Among authors: barabasi al. Nat Biotechnol. 2007 Oct;25(10):1119-26. doi: 10.1038/nbt1338. Nat Biotechnol. 2007. PMID: 17921997
Predicting synthetic rescues in metabolic networks.
Motter AE, Gulbahce N, Almaas E, Barabási AL. Motter AE, et al. Among authors: barabasi al. Mol Syst Biol. 2008;4:168. doi: 10.1038/msb.2008.1. Epub 2008 Feb 12. Mol Syst Biol. 2008. PMID: 18277384 Free PMC article.
High-quality binary protein interaction map of the yeast interactome network.
Yu H, Braun P, Yildirim MA, Lemmens I, Venkatesan K, Sahalie J, Hirozane-Kishikawa T, Gebreab F, Li N, Simonis N, Hao T, Rual JF, Dricot A, Vazquez A, Murray RR, Simon C, Tardivo L, Tam S, Svrzikapa N, Fan C, de Smet AS, Motyl A, Hudson ME, Park J, Xin X, Cusick ME, Moore T, Boone C, Snyder M, Roth FP, Barabási AL, Tavernier J, Hill DE, Vidal M. Yu H, et al. Among authors: barabasi al. Science. 2008 Oct 3;322(5898):104-10. doi: 10.1126/science.1158684. Epub 2008 Aug 21. Science. 2008. PMID: 18719252 Free PMC article.
An empirical framework for binary interactome mapping.
Venkatesan K, Rual JF, Vazquez A, Stelzl U, Lemmens I, Hirozane-Kishikawa T, Hao T, Zenkner M, Xin X, Goh KI, Yildirim MA, Simonis N, Heinzmann K, Gebreab F, Sahalie JM, Cevik S, Simon C, de Smet AS, Dann E, Smolyar A, Vinayagam A, Yu H, Szeto D, Borick H, Dricot A, Klitgord N, Murray RR, Lin C, Lalowski M, Timm J, Rau K, Boone C, Braun P, Cusick ME, Roth FP, Hill DE, Tavernier J, Wanker EE, Barabási AL, Vidal M. Venkatesan K, et al. Among authors: barabasi al. Nat Methods. 2009 Jan;6(1):83-90. doi: 10.1038/nmeth.1280. Epub 2008 Dec 7. Nat Methods. 2009. PMID: 19060904 Free PMC article.
The impact of cellular networks on disease comorbidity.
Park J, Lee DS, Christakis NA, Barabási AL. Park J, et al. Among authors: barabasi al. Mol Syst Biol. 2009;5:262. doi: 10.1038/msb.2009.16. Epub 2009 Apr 7. Mol Syst Biol. 2009. PMID: 19357641 Free PMC article.
Interactome networks and human disease.
Vidal M, Cusick ME, Barabási AL. Vidal M, et al. Among authors: barabasi al. Cell. 2011 Mar 18;144(6):986-98. doi: 10.1016/j.cell.2011.02.016. Cell. 2011. PMID: 21414488 Free PMC article. Review.
242 results