Acquisition of hormone-independent growth in MCF-7 cells is accompanied by increased expression of estrogen-regulated genes but without detectable DNA amplifications.
Brünner N, Boulay V, Fojo A, Freter CE, Lippman ME, Clarke R.
Brünner N, et al. Among authors: clarke r.
Cancer Res. 1993 Jan 15;53(2):283-90.
Cancer Res. 1993.
PMID: 8380254
A hormone-independent but hormone-responsive subpopulation (MCF7/MIII) of the hormone-dependent MCF-7 human breast cancer cell line (R. Clarke et al., Proc. Natl. Acad. Sci. USA 86: 3649-3653, 1989) was further passaged in ovariectomized nude mice and re-established …
A hormone-independent but hormone-responsive subpopulation (MCF7/MIII) of the hormone-dependent MCF-7 human breast cancer cell line (R …