Antonescu CR - Search Results

1

Combined inhibition of MAP kinase and KIT signaling synergistically destabilizes ETV1 and suppresses GIST tumor growth.

Ran L, Sirota I, Cao Z, Murphy D, Chen Y, Shukla S, Xie Y, Kaufmann MC, Gao D, Zhu S, Rossi F, Wongvipat J, Taguchi T, Tap WD, Mellinghoff IK, Besmer P, Antonescu CR, Chen Y, Chi P. Ran L, et al. Among authors: antonescu cr. Cancer Discov. 2015 Mar;5(3):304-15. doi: 10.1158/2159-8290.CD-14-0985. Epub 2015 Jan 8. Cancer Discov. 2015. PMID: 25572173 Free PMC article.

2

Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase.

Sommer G, Agosti V, Ehlers I, Rossi F, Corbacioglu S, Farkas J, Moore M, Manova K, Antonescu CR, Besmer P. Sommer G, et al. Among authors: antonescu cr. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6706-11. doi: 10.1073/pnas.1037763100. Epub 2003 May 16. Proc Natl Acad Sci U S A. 2003. PMID: 12754375 Free PMC article.

3

Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors.

Antonescu CR, Sommer G, Sarran L, Tschernyavsky SJ, Riedel E, Woodruff JM, Robson M, Maki R, Brennan MF, Ladanyi M, DeMatteo RP, Besmer P. Antonescu CR, et al. Clin Cancer Res. 2003 Aug 15;9(9):3329-37. Clin Cancer Res. 2003. PMID: 12960119

4

Pleomorphic characteristics of a germ-line KIT mutation in a large kindred with gastrointestinal stromal tumors, hyperpigmentation, and dysphagia.

Robson ME, Glogowski E, Sommer G, Antonescu CR, Nafa K, Maki RG, Ellis N, Besmer P, Brennan M, Offit K. Robson ME, et al. Among authors: antonescu cr. Clin Cancer Res. 2004 Feb 15;10(4):1250-4. doi: 10.1158/1078-0432.ccr-03-0110. Clin Cancer Res. 2004. PMID: 14977822

5

Gene expression in gastrointestinal stromal tumors is distinguished by KIT genotype and anatomic site.

Antonescu CR, Viale A, Sarran L, Tschernyavsky SJ, Gonen M, Segal NH, Maki RG, Socci ND, DeMatteo RP, Besmer P. Antonescu CR, et al. Clin Cancer Res. 2004 May 15;10(10):3282-90. doi: 10.1158/1078-0432.CCR-03-0715. Clin Cancer Res. 2004. PMID: 15161681

6

Multiple gastrointestinal stromal tumors in type I neurofibromatosis: a pathologic and molecular study.

Yantiss RK, Rosenberg AE, Sarran L, Besmer P, Antonescu CR. Yantiss RK, et al. Among authors: antonescu cr. Mod Pathol. 2005 Apr;18(4):475-84. doi: 10.1038/modpathol.3800334. Mod Pathol. 2005. PMID: 15540118 Free article.

7

Gastrointestinal stromal tumors in children and young adults: a clinicopathologic, molecular, and genomic study of 15 cases and review of the literature.

Prakash S, Sarran L, Socci N, DeMatteo RP, Eisenstat J, Greco AM, Maki RG, Wexler LH, LaQuaglia MP, Besmer P, Antonescu CR. Prakash S, et al. Among authors: antonescu cr. J Pediatr Hematol Oncol. 2005 Apr;27(4):179-87. doi: 10.1097/01.mph.0000157790.81329.47. J Pediatr Hematol Oncol. 2005. PMID: 15838387 Review.

8

Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation.

Antonescu CR, Besmer P, Guo T, Arkun K, Hom G, Koryotowski B, Leversha MA, Jeffrey PD, Desantis D, Singer S, Brennan MF, Maki RG, DeMatteo RP. Antonescu CR, et al. Clin Cancer Res. 2005 Jun 1;11(11):4182-90. doi: 10.1158/1078-0432.CCR-04-2245. Clin Cancer Res. 2005. PMID: 15930355

9

A knock-in mouse model of gastrointestinal stromal tumor harboring kit K641E.

Rubin BP, Antonescu CR, Scott-Browne JP, Comstock ML, Gu Y, Tanas MR, Ware CB, Woodell J. Rubin BP, et al. Among authors: antonescu cr. Cancer Res. 2005 Aug 1;65(15):6631-9. doi: 10.1158/0008-5472.CAN-05-0891. Cancer Res. 2005. PMID: 16061643

10

Oncogenic Kit signaling and therapeutic intervention in a mouse model of gastrointestinal stromal tumor.

Rossi F, Ehlers I, Agosti V, Socci ND, Viale A, Sommer G, Yozgat Y, Manova K, Antonescu CR, Besmer P. Rossi F, et al. Among authors: antonescu cr. Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12843-8. doi: 10.1073/pnas.0511076103. Epub 2006 Aug 14. Proc Natl Acad Sci U S A. 2006. PMID: 16908864 Free PMC article.

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