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Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance.
Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, Coulter S, Liddle C, Schoonjans K, Olefsky JM, Saltiel AR, Downes M, Evans RM. Fang S, et al. Nat Med. 2015 Feb;21(2):159-65. doi: 10.1038/nm.3760. Epub 2015 Jan 5. Nat Med. 2015. PMID: 25559344 Free PMC article.
Depletion of fat-resident Treg cells prevents age-associated insulin resistance.
Bapat SP, Myoung Suh J, Fang S, Liu S, Zhang Y, Cheng A, Zhou C, Liang Y, LeBlanc M, Liddle C, Atkins AR, Yu RT, Downes M, Evans RM, Zheng Y. Bapat SP, et al. Among authors: fang s. Nature. 2015 Dec 3;528(7580):137-41. doi: 10.1038/nature16151. Epub 2015 Nov 18. Nature. 2015. PMID: 26580014 Free PMC article.
FXR Regulates Intestinal Cancer Stem Cell Proliferation.
Fu T, Coulter S, Yoshihara E, Oh TG, Fang S, Cayabyab F, Zhu Q, Zhang T, Leblanc M, Liu S, He M, Waizenegger W, Gasser E, Schnabl B, Atkins AR, Yu RT, Knight R, Liddle C, Downes M, Evans RM. Fu T, et al. Among authors: fang s. Cell. 2019 Feb 21;176(5):1098-1112.e18. doi: 10.1016/j.cell.2019.01.036. Cell. 2019. PMID: 30794774 Free PMC article.
Microbiology: Wealth management in the gut.
Fang S, Evans RM. Fang S, et al. Nature. 2013 Aug 29;500(7464):538-9. doi: 10.1038/500538a. Nature. 2013. PMID: 23985869 No abstract available.
Vitamin D Switches BAF Complexes to Protect β Cells.
Wei Z, Yoshihara E, He N, Hah N, Fan W, Pinto AFM, Huddy T, Wang Y, Ross B, Estepa G, Dai Y, Ding N, Sherman MH, Fang S, Zhao X, Liddle C, Atkins AR, Yu RT, Downes M, Evans RM. Wei Z, et al. Among authors: fang s. Cell. 2018 May 17;173(5):1135-1149.e15. doi: 10.1016/j.cell.2018.04.013. Epub 2018 May 10. Cell. 2018. PMID: 29754817 Free PMC article.
Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis.
Hong SH, Fang S, Lu BC, Nofsinger R, Kawakami Y, Castro GL, Yin Y, Lin C, Yu RT, Downes M, Izpisúa Belmonte JC, Shilatifard A, Evans RM. Hong SH, et al. Among authors: fang s. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10381-10386. doi: 10.1073/pnas.1809480115. Epub 2018 Sep 25. Proc Natl Acad Sci U S A. 2018. PMID: 30254164 Free PMC article.
5,636 results