Bailey FP - Search Results

1

Going for broke: targeting the human cancer pseudokinome.

Bailey FP, Byrne DP, McSkimming D, Kannan N, Eyers PA. Bailey FP, et al. Biochem J. 2015 Jan 15;465(2):195-211. doi: 10.1042/BJ20141060. Biochem J. 2015. PMID: 25559089 Review.

2

2) Going for broke: targeting the human cancer pseudokinome.

Bailey FP, Byrne DP, McSkimming D, Kannan N, Eyers PA. Bailey FP, et al. Biochem J. 2015 Feb 15;466(1):201. doi: 10.1042/bj4660201v. Biochem J. 2015. PMID: 25656056 No abstract available.

3

A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties.

Murphy JM, Zhang Q, Young SN, Reese ML, Bailey FP, Eyers PA, Ungureanu D, Hammaren H, Silvennoinen O, Varghese LN, Chen K, Tripaydonis A, Jura N, Fukuda K, Qin J, Nimchuk Z, Mudgett MB, Elowe S, Gee CL, Liu L, Daly RJ, Manning G, Babon JJ, Lucet IS. Murphy JM, et al. Among authors: bailey fp. Biochem J. 2014 Jan 15;457(2):323-34. doi: 10.1042/BJ20131174. Biochem J. 2014. PMID: 24107129 Free PMC article.

4

The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner.

Bailey FP, Byrne DP, Oruganty K, Eyers CE, Novotny CJ, Shokat KM, Kannan N, Eyers PA. Bailey FP, et al. Biochem J. 2015 Apr 1;467(1):47-62. doi: 10.1042/BJ20141441. Biochem J. 2015. PMID: 25583260 Free PMC article.

5

Tribbles pseudokinases: novel targets for chemical biology and drug discovery?

Foulkes DM, Byrne DP, Bailey FP, Eyers PA. Foulkes DM, et al. Among authors: bailey fp. Biochem Soc Trans. 2015 Oct;43(5):1095-103. doi: 10.1042/BST20150109. Biochem Soc Trans. 2015. PMID: 26517930 Review.

6

The resistance tetrad: amino acid hotspots for kinome-wide exploitation of drug-resistant protein kinase alleles.

Bailey FP, Andreev VI, Eyers PA. Bailey FP, et al. Methods Enzymol. 2014;548:117-46. doi: 10.1016/B978-0-12-397918-6.00005-7. Methods Enzymol. 2014. PMID: 25399644 Review.

7

The hVps34-SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth.

Bago R, Sommer E, Castel P, Crafter C, Bailey FP, Shpiro N, Baselga J, Cross D, Eyers PA, Alessi DR. Bago R, et al. Among authors: bailey fp. EMBO J. 2016 Sep 1;35(17):1902-22. doi: 10.15252/embj.201693929. Epub 2016 Aug 1. EMBO J. 2016. PMID: 27481935 Free PMC article.

8

Kinome-wide transcriptional profiling of uveal melanoma reveals new vulnerabilities to targeted therapeutics.

Bailey FP, Clarke K, Kalirai H, Kenyani J, Shahidipour H, Falciani F, Coulson JM, Sacco JJ, Coupland SE, Eyers PA. Bailey FP, et al. Pigment Cell Melanoma Res. 2018 Mar;31(2):253-266. doi: 10.1111/pcmr.12650. Epub 2017 Oct 15. Pigment Cell Melanoma Res. 2018. PMID: 28972303 Review.

9

Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells.

Foulkes DM, Byrne DP, Yeung W, Shrestha S, Bailey FP, Ferries S, Eyers CE, Keeshan K, Wells C, Drewry DH, Zuercher WJ, Kannan N, Eyers PA. Foulkes DM, et al. Among authors: bailey fp. Sci Signal. 2018 Sep 25;11(549):eaat7951. doi: 10.1126/scisignal.aat7951. Sci Signal. 2018. PMID: 30254057 Free PMC article.

10

Towards 20,20-difluorinated bryostatin: synthesis and biological evaluation of C17,C27-fragments.

Mears PR, Hoekman S, Rye CE, Bailey FP, Byrne DP, Eyers PA, Thomas EJ. Mears PR, et al. Among authors: bailey fp. Org Biomol Chem. 2019 Feb 6;17(6):1487-1505. doi: 10.1039/c8ob03152e. Org Biomol Chem. 2019. PMID: 30681118

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