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Use of next-generation sequencing and candidate gene analysis to identify underlying defects in patients with inherited platelet function disorders.
Leo VC, Morgan NV, Bem D, Jones ML, Lowe GC, Lordkipanidzé M, Drake S, Simpson MA, Gissen P, Mumford A, Watson SP, Daly ME; UK GAPP Study Group. Leo VC, et al. Among authors: lordkipanidze m. J Thromb Haemost. 2015 Apr;13(4):643-50. doi: 10.1111/jth.12836. Epub 2015 Jan 27. J Thromb Haemost. 2015. PMID: 25556537 Free PMC article.
Megakaryocytes possess a STING pathway that is transferred to platelets to potentiate activation.
El-Mortada F, Landelouci K, Bertrand-Perron S, Aubé FA, Poirier A, Bidias A, Jourdi G, Welman M, Gantier MP, Hamilton JR, Kile B, Lordkipanidzé M, Pépin G. El-Mortada F, et al. Among authors: lordkipanidze m. Life Sci Alliance. 2023 Nov 22;7(2):e202302211. doi: 10.26508/lsa.202302211. Print 2024 Feb. Life Sci Alliance. 2023. PMID: 37993259 Free PMC article.
Plasminogen Activator Inhibitor-1-Positive Platelet-Derived Extracellular Vesicles Predicts MACE and the Proinflammatory SMC Phenotype.
Jung RG, Duchez AC, Simard T, Dhaliwal S, Gillmore T, Di Santo P, Labinaz A, Ramirez FD, Rasheed A, Robichaud S, Ouimet M, Short S, Clifford C, Xiao F, Lordkipanidzé M, Burger D, Gadde S, Rayner KJ, Hibbert B. Jung RG, et al. Among authors: lordkipanidze m. JACC Basic Transl Sci. 2022 Sep 21;7(10):985-997. doi: 10.1016/j.jacbts.2022.05.002. eCollection 2022 Oct. JACC Basic Transl Sci. 2022. PMID: 36337926 Free PMC article.
Beware of being caught on the rebound.
Lordkipanidzé M, Harrison P. Lordkipanidzé M, et al. J Thromb Haemost. 2011 Jan;9(1):21-3. doi: 10.1111/j.1538-7836.2010.04125.x. J Thromb Haemost. 2011. PMID: 21210949 Free article. No abstract available.
Aspirin twice a day keeps new COX-1 at bay.
Lordkipanidzé M, Harrison P. Lordkipanidzé M, et al. J Thromb Haemost. 2012 Jul;10(7):1217-9. doi: 10.1111/j.1538-7836.2012.04764.x. J Thromb Haemost. 2012. PMID: 22540218 Free article. No abstract available.
G6f-like is an ITAM-containing collagen receptor in thrombocytes.
Hughes CE, Radhakrishnan UP, Lordkipanidzé M, Egginton S, Dijkstra JM, Jagadeeswaran P, Watson SP. Hughes CE, et al. Among authors: lordkipanidze m. PLoS One. 2012;7(12):e52622. doi: 10.1371/journal.pone.0052622. Epub 2012 Dec 21. PLoS One. 2012. PMID: 23285115 Free PMC article.
Microsatellite markers as a rapid approach for autozygosity mapping in Hermansky-Pudlak syndrome: identification of the second HPS7 mutation in a patient presenting late in life.
Lowe GC, Sánchez Guiu I, Chapman O, Rivera J, Lordkipanidzé M, Dovlatova N, Wilde J, Watson SP, Morgan NV; UK GAPP collaborative. Lowe GC, et al. Among authors: lordkipanidze m. Thromb Haemost. 2013 Apr;109(4):766-8. doi: 10.1160/TH12-11-0876. Epub 2013 Jan 31. Thromb Haemost. 2013. PMID: 23364359 Free PMC article.
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