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Loss of Sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays PARK2 translocation to mitochondria.
Di Sante G, Pestell TG, Casimiro MC, Bisetto S, Powell MJ, Lisanti MP, Cordon-Cardo C, Castillo-Martin M, Bonal DM, Debattisti V, Chen K, Wang L, He X, McBurney MW, Pestell RG. Di Sante G, et al. Among authors: mcburney mw. Am J Pathol. 2015 Jan;185(1):266-79. doi: 10.1016/j.ajpath.2014.09.014. Am J Pathol. 2015. PMID: 25529796 Free PMC article.
SirT1 fails to affect p53-mediated biological functions.
Kamel C, Abrol M, Jardine K, He X, McBurney MW. Kamel C, et al. Among authors: mcburney mw. Aging Cell. 2006 Feb;5(1):81-8. doi: 10.1111/j.1474-9726.2006.00191.x. Aging Cell. 2006. PMID: 16441846 Free article.
Reversible modulation of SIRT1 activity in a mouse strain.
Clark-Knowles KV, He X, Jardine K, Coulombe J, Dewar-Darch D, Caron AZ, Gray DA, McBurney MW. Clark-Knowles KV, et al. Among authors: mcburney mw. PLoS One. 2017 Mar 8;12(3):e0173002. doi: 10.1371/journal.pone.0173002. eCollection 2017. PLoS One. 2017. PMID: 28273169 Free PMC article.
sirt1-null mice develop an autoimmune-like condition.
Sequeira J, Boily G, Bazinet S, Saliba S, He X, Jardine K, Kennedy C, Staines W, Rousseaux C, Mueller R, McBurney MW. Sequeira J, et al. Among authors: mcburney mw. Exp Cell Res. 2008 Oct 1;314(16):3069-74. doi: 10.1016/j.yexcr.2008.07.011. Epub 2008 Jul 23. Exp Cell Res. 2008. PMID: 18687325
173 results