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Inhibition of choroidal neovascularization in a nonhuman primate model by intravitreal administration of an AAV2 vector expressing a novel anti-VEGF molecule.
Lukason M, DuFresne E, Rubin H, Pechan P, Li Q, Kim I, Kiss S, Flaxel C, Collins M, Miller J, Hauswirth W, Maclachlan T, Wadsworth S, Scaria A. Lukason M, et al. Among authors: pechan p. Mol Ther. 2011 Feb;19(2):260-5. doi: 10.1038/mt.2010.230. Epub 2010 Oct 26. Mol Ther. 2011. PMID: 20978476 Free PMC article.
sFLT01: a novel fusion protein with antiangiogenic activity.
Bagley RG, Kurtzberg L, Weber W, Nguyen TH, Roth S, Krumbholz R, Yao M, Richards B, Zhang M, Pechan P, Schmid S, Scaria A, Kaplan J, Teicher BA. Bagley RG, et al. Among authors: pechan p. Mol Cancer Ther. 2011 Mar;10(3):404-15. doi: 10.1158/1535-7163.MCT-10-0813. Epub 2011 Jan 20. Mol Cancer Ther. 2011. PMID: 21252283
Aurintricarboxylic acid increases yield of HSV-1 vectors.
Pechan P, Ardinger J, Ketavarapu J, Rubin H, Wadsworth SC, Scaria A. Pechan P, et al. Mol Ther Methods Clin Dev. 2014 Feb 19;1:6. doi: 10.1038/mtm.2013.6. eCollection 2014. Mol Ther Methods Clin Dev. 2014. PMID: 26015945 Free PMC article.
Gene therapy for brain tumors.
Kramm CM, Sena-Esteves M, Barnett FH, Rainov NG, Schuback DE, Yu JS, Pechan PA, Paulus W, Chiocca EA, Breakefield XO. Kramm CM, et al. Among authors: pechan pa. Brain Pathol. 1995 Oct;5(4):345-81. doi: 10.1111/j.1750-3639.1995.tb00615.x. Brain Pathol. 1995. PMID: 8974620 Review.
Targeting gene therapy vectors to CNS malignancies.
Spear MA, Herrlinger U, Rainov N, Pechan P, Weissleder R, Breakefield XO. Spear MA, et al. Among authors: pechan p. J Neurovirol. 1998 Apr;4(2):133-47. doi: 10.3109/13550289809114514. J Neurovirol. 1998. PMID: 9584951 Review.
46 results