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Five birds, one stone: neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody.
Rouha H, Badarau A, Visram ZC, Battles MB, Prinz B, Magyarics Z, Nagy G, Mirkina I, Stulik L, Zerbs M, Jägerhofer M, Maierhofer B, Teubenbacher A, Dolezilkova I, Gross K, Banerjee S, Zauner G, Malafa S, Zmajkovic J, Maier S, Mabry R, Krauland E, Wittrup KD, Gerngross TU, Nagy E. Rouha H, et al. Among authors: teubenbacher a. MAbs. 2015;7(1):243-54. doi: 10.4161/19420862.2014.985132. MAbs. 2015. PMID: 25523282 Free PMC article.
Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi-component toxin LukGH.
Badarau A, Rouha H, Malafa S, Logan DT, Håkansson M, Stulik L, Dolezilkova I, Teubenbacher A, Gross K, Maierhofer B, Weber S, Jägerhofer M, Hoffman D, Nagy E. Badarau A, et al. Among authors: teubenbacher a. J Biol Chem. 2015 Jan 2;290(1):142-56. doi: 10.1074/jbc.M114.598110. Epub 2014 Nov 3. J Biol Chem. 2015. PMID: 25371205 Free PMC article.
Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies.
Badarau A, Rouha H, Malafa S, Battles MB, Walker L, Nielson N, Dolezilkova I, Teubenbacher A, Banerjee S, Maierhofer B, Weber S, Stulik L, Logan DT, Welin M, Mirkina I, Pleban C, Zauner G, Gross K, Jägerhofer M, Magyarics Z, Nagy E. Badarau A, et al. Among authors: teubenbacher a. MAbs. 2016 Oct;8(7):1347-1360. doi: 10.1080/19420862.2016.1215791. Epub 2016 Jul 28. MAbs. 2016. PMID: 27467113 Free PMC article.