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The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable.
Benod C, Villagomez R, Filgueira CS, Hwang PK, Leonard PG, Poncet-Montange G, Rajagopalan S, Fletterick RJ, Gustafsson JÅ, Webb P. Benod C, et al. Among authors: webb p. PLoS One. 2014 Jun 17;9(6):e99440. doi: 10.1371/journal.pone.0099440. eCollection 2014. PLoS One. 2014. PMID: 24936658 Free PMC article.
Editorial.
Gustafsson JA, Webb P. Gustafsson JA, et al. Among authors: webb p. J Steroid Biochem Mol Biol. 2016 Mar;157:1-2. doi: 10.1016/j.jsbmb.2015.12.027. J Steroid Biochem Mol Biol. 2016. PMID: 26791250
A screening cascade to identify ERβ ligands.
Filgueira CS, Benod C, Lou X, Gunamalai PS, Villagomez RA, Strom A, Gustafsson JÅ, Berkenstam AL, Webb P. Filgueira CS, et al. Among authors: webb p. Nucl Recept Signal. 2014 Nov 4;12:e003. doi: 10.1621/nrs.12003. eCollection 2014. Nucl Recept Signal. 2014. PMID: 25422593 Free PMC article.
1,348 results