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microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis.
de Guia RM, Rose AJ, Sommerfeld A, Seibert O, Strzoda D, Zota A, Feuchter Y, Krones-Herzig A, Sijmonsma T, Kirilov M, Sticht C, Gretz N, Dallinga-Thie G, Diederichs S, Klöting N, Blüher M, Berriel Diaz M, Herzig S. de Guia RM, et al. EMBO J. 2015 Feb 3;34(3):344-60. doi: 10.15252/embj.201490464. Epub 2014 Dec 15. EMBO J. 2015. PMID: 25510864 Free PMC article. Clinical Trial.
Fasting-induced liver GADD45β restrains hepatic fatty acid uptake and improves metabolic health.
Fuhrmeister J, Zota A, Sijmonsma TP, Seibert O, Cıngır Ş, Schmidt K, Vallon N, de Guia RM, Niopek K, Berriel Diaz M, Maida A, Blüher M, Okun JG, Herzig S, Rose AJ. Fuhrmeister J, et al. Among authors: de guia rm. EMBO Mol Med. 2016 Jun 1;8(6):654-69. doi: 10.15252/emmm.201505801. Print 2016 Jun. EMBO Mol Med. 2016. PMID: 27137487 Free PMC article.
Glucocorticoid hormones and energy homeostasis.
de Guia RM, Rose AJ, Herzig S. de Guia RM, et al. Horm Mol Biol Clin Investig. 2014 Aug;19(2):117-28. doi: 10.1515/hmbci-2014-0021. Horm Mol Biol Clin Investig. 2014. PMID: 25390020 Review.
Molecular regulation of urea cycle function by the liver glucocorticoid receptor.
Okun JG, Conway S, Schmidt KV, Schumacher J, Wang X, de Guia R, Zota A, Klement J, Seibert O, Peters A, Maida A, Herzig S, Rose AJ. Okun JG, et al. Mol Metab. 2015 Jul 30;4(10):732-40. doi: 10.1016/j.molmet.2015.07.006. eCollection 2015 Oct. Mol Metab. 2015. PMID: 26500844 Free PMC article.
Trip13 Depletion in Liver Cancer Induces a Lipogenic Response Contributing to Plin2-Dependent Mitotic Cell Death.
Rios Garcia M, Meissburger B, Chan J, de Guia RM, Mattijssen F, Roessler S, Birkenfeld AL, Raschzok N, Riols F, Tokarz J, Giroud M, Gil Lozano M, Hartleben G, Nawroth P, Haid M, López M, Herzig S, Berriel Diaz M. Rios Garcia M, et al. Among authors: de guia rm. Adv Sci (Weinh). 2022 Oct;9(29):e2104291. doi: 10.1002/advs.202104291. Epub 2022 Aug 28. Adv Sci (Weinh). 2022. PMID: 36031387 Free PMC article.
Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity.
Basse AL, Agerholm M, Farup J, Dalbram E, Nielsen J, Ørtenblad N, Altıntaş A, Ehrlich AM, Krag T, Bruzzone S, Dall M, de Guia RM, Jensen JB, Møller AB, Karlsen A, Kjær M, Barrès R, Vissing J, Larsen S, Jessen N, Treebak JT. Basse AL, et al. Among authors: de guia rm. Mol Metab. 2021 Nov;53:101271. doi: 10.1016/j.molmet.2021.101271. Epub 2021 Jun 11. Mol Metab. 2021. PMID: 34119711 Free PMC article.
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