Hocková D - Search Results

1

Aza-acyclic nucleoside phosphonates containing a second phosphonate group as inhibitors of the human, Plasmodium falciparum and vivax 6-oxopurine phosphoribosyltransferases and their prodrugs as antimalarial agents.

Keough DT, Hocková D, Janeba Z, Wang TH, Naesens L, Edstein MD, Chavchich M, Guddat LW. Keough DT, et al. Among authors: hockova d. J Med Chem. 2015 Jan 22;58(2):827-46. doi: 10.1021/jm501416t. Epub 2014 Dec 24. J Med Chem. 2015. PMID: 25494538

2

5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidines-acyclic nucleoside phosphonate analogues with antiviral activity.

Hocková D, Holý A, Masojídková M, Andrei G, Snoeck R, De Clercq E, Balzarini J. Hocková D, et al. J Med Chem. 2003 Nov 6;46(23):5064-73. doi: 10.1021/jm030932o. J Med Chem. 2003. PMID: 14584956

3

6-[2-phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines: a new class of acyclic pyrimidine nucleoside phosphonates with antiviral activity.

Balzarini J, Pannecouque C, Naesens L, Andrei G, Snoeck R, De Clercq E, Hocková D, Holý A. Balzarini J, et al. Among authors: hockova d. Nucleosides Nucleotides Nucleic Acids. 2004 Oct;23(8-9):1321-7. doi: 10.1081/NCN-200027573. Nucleosides Nucleotides Nucleic Acids. 2004. PMID: 15571252

4

Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines.

De Clercq E, Andrei G, Balzarini J, Leyssen P, Naesens L, Neyts J, Pannecouque C, Snoeck R, Ying C, Hocková D, Holý A. De Clercq E, et al. Among authors: hockova d. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):331-41. doi: 10.1081/ncn-200059772. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16247948

5

Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics.

Keough DT, Hocková D, Holý A, Naesens LM, Skinner-Adams TS, Jersey Jd, Guddat LW. Keough DT, et al. Among authors: hockova d. J Med Chem. 2009 Jul 23;52(14):4391-9. doi: 10.1021/jm900267n. J Med Chem. 2009. PMID: 19527031

6

Synthesis of branched 9-[2-(2-phosphonoethoxy)ethyl]purines as a new class of acyclic nucleoside phosphonates which inhibit Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.

Hocková D, Holý A, Masojídková M, Keough DT, de Jersey J, Guddat LW. Hocková D, et al. Bioorg Med Chem. 2009 Sep 1;17(17):6218-32. doi: 10.1016/j.bmc.2009.07.044. Epub 2009 Jul 25. Bioorg Med Chem. 2009. PMID: 19666228

7

Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase: a target for anti-malarial chemotherapy.

Keough DT, Hocková D, Krecmerová M, Cesnek M, Holý A, Naesens L, Brereton IM, Winzor DJ, de Jersey J, Guddat LW. Keough DT, et al. Among authors: hockova d. Mol Biochem Parasitol. 2010 Oct;173(2):165-9. doi: 10.1016/j.molbiopara.2010.05.018. Epub 2010 Jun 1. Mol Biochem Parasitol. 2010. PMID: 20595032 Free article.

8

6-oxopurine phosphoribosyltransferase: a target for the development of antimalarial drugs.

de Jersey J, Holý A, Hocková D, Naesens L, Keough DT, Guddat LW. de Jersey J, et al. Among authors: hockova d. Curr Top Med Chem. 2011;11(16):2085-102. doi: 10.2174/156802611796575911. Curr Top Med Chem. 2011. PMID: 21619515 Free article. Review.

9

Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: efficient synthesis and antiviral activity.

Hocková D, Holý A, Andrei G, Snoeck R, Balzarini J. Hocková D, et al. Bioorg Med Chem. 2011 Aug 1;19(15):4445-53. doi: 10.1016/j.bmc.2011.06.045. Epub 2011 Jun 22. Bioorg Med Chem. 2011. PMID: 21745746 Free PMC article.

10

Synthesis of 9-phosphonoalkyl and 9-phosphonoalkoxyalkyl purines: evaluation of their ability to act as inhibitors of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases.

Česnek M, Hocková D, Holý A, Dračínský M, Baszczyňski O, Jersey Jd, Keough DT, Guddat LW. Česnek M, et al. Among authors: hockova d. Bioorg Med Chem. 2012 Jan 15;20(2):1076-89. doi: 10.1016/j.bmc.2011.11.034. Epub 2011 Dec 1. Bioorg Med Chem. 2012. PMID: 22178188

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