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Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP.
Kusuhara H, Furuie H, Inano A, Sunagawa A, Yamada S, Wu C, Fukizawa S, Morimoto N, Ieiri I, Morishita M, Sumita K, Mayahara H, Fujita T, Maeda K, Sugiyama Y. Kusuhara H, et al. Among authors: ieiri i. Br J Pharmacol. 2012 Jul;166(6):1793-803. doi: 10.1111/j.1476-5381.2012.01887.x. Br J Pharmacol. 2012. PMID: 22300367 Free PMC article. Clinical Trial.
Mechanisms of pharmacokinetic enhancement between ritonavir and saquinavir; micro/small dosing tests using midazolam (CYP3A4), fexofenadine (p-glycoprotein), and pravastatin (OATP1B1) as probe drugs.
Ieiri I, Tsunemitsu S, Maeda K, Ando Y, Izumi N, Kimura M, Yamane N, Okuzono T, Morishita M, Kotani N, Kanda E, Deguchi M, Matsuguma K, Matsuki S, Hirota T, Irie S, Kusuhara H, Sugiyama Y. Ieiri I, et al. J Clin Pharmacol. 2013 Jun;53(6):654-61. doi: 10.1002/jcph.62. Epub 2013 Feb 4. J Clin Pharmacol. 2013. PMID: 23381882 Clinical Trial.
Modeling and simulation of bone mineral density response from a phase 2 study of ONO-5334, a new cathepsin K inhibitor, to support dose selection in osteoporosis.
Hasegawa C, Kastrissios H, Monteleone J, Ohno T, Umemura T, Ohyama M, Nagase S, Small M, Deacon S, Ogawa M, Ieiri I. Hasegawa C, et al. Among authors: ieiri i. J Clin Pharmacol. 2014 Aug;54(8):937-48. doi: 10.1002/jcph.279. Epub 2014 Feb 28. J Clin Pharmacol. 2014. PMID: 24615681 Clinical Trial.
198 results