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467 results

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RXR partial agonist produced by side chain repositioning of alkoxy RXR full agonist retains antitype 2 diabetes activity without the adverse effects.
Kawata K, Morishita K, Nakayama M, Yamada S, Kobayashi T, Furusawa Y, Arimoto-Kobayashi S, Oohashi T, Makishima M, Naitou H, Ishitsubo E, Tokiwa H, Tai A, Kakuta H. Kawata K, et al. Among authors: furusawa y. J Med Chem. 2015 Jan 22;58(2):912-26. doi: 10.1021/jm501863r. Epub 2014 Dec 17. J Med Chem. 2015. PMID: 25486327
Nrf2 induces fibroblast growth factor 21 in diabetic mice.
Furusawa Y, Uruno A, Yagishita Y, Higashi C, Yamamoto M. Furusawa Y, et al. Genes Cells. 2014 Dec;19(12):864-78. doi: 10.1111/gtc.12186. Epub 2014 Oct 1. Genes Cells. 2014. PMID: 25270507 Free article.
The Keap1-Nrf2 system prevents onset of diabetes mellitus.
Uruno A, Furusawa Y, Yagishita Y, Fukutomi T, Muramatsu H, Negishi T, Sugawara A, Kensler TW, Yamamoto M. Uruno A, et al. Among authors: furusawa y. Mol Cell Biol. 2013 Aug;33(15):2996-3010. doi: 10.1128/MCB.00225-13. Epub 2013 May 28. Mol Cell Biol. 2013. PMID: 23716596 Free PMC article.
Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response.
Saito R, Suzuki T, Hiramoto K, Asami S, Naganuma E, Suda H, Iso T, Yamamoto H, Morita M, Baird L, Furusawa Y, Negishi T, Ichinose M, Yamamoto M. Saito R, et al. Among authors: furusawa y. Mol Cell Biol. 2015 Nov 2;36(2):271-84. doi: 10.1128/MCB.00868-15. Print 2016 Jan 15. Mol Cell Biol. 2015. PMID: 26527616 Free PMC article.
228Ra/226Ra ratio and 7Be concentration in the Sea of Japan as indicators for water transport: comparison with migration pattern of Fukushima Dai-ichi NPP-derived 134Cs and 137Cs.
Inoue M, Furusawa Y, Fujimoto K, Minakawa M, Kofuji H, Nagao S, Yamamoto M, Hamajima Y, Yoshida K, Nakano Y, Hayakawa K, Oikawa S, Misonoo J, Isoda Y. Inoue M, et al. Among authors: furusawa y. J Environ Radioact. 2013 Dec;126:176-87. doi: 10.1016/j.jenvrad.2013.08.001. Epub 2013 Sep 10. J Environ Radioact. 2013. PMID: 24029140
An orally available P1'-5-fluorinated Mpro inhibitor blocks SARS-CoV-2 replication without booster and exhibits high genetic barrier.
Higashi-Kuwata N, Bulut H, Hayashi H, Tsuji K, Ogata-Aoki H, Kiso M, Takamune N, Kishimoto N, Hattori SI, Ishii T, Kobayakawa T, Nakano K, Shimizu Y, Das D, Saruwatari J, Hasegawa K, Murayama K, Sukenaga Y, Takamatsu Y, Yoshimura K, Aoki M, Furusawa Y, Okamura T, Yamayoshi S, Kawaoka Y, Misumi S, Tamamura H, Mitsuya H. Higashi-Kuwata N, et al. Among authors: furusawa y. PNAS Nexus. 2025 Jan 7;4(1):pgae578. doi: 10.1093/pnasnexus/pgae578. eCollection 2025 Jan. PNAS Nexus. 2025. PMID: 39831159 Free PMC article.
Hydroxylated-Benz[a]anthracenes Induce Two Apoptosis-Related Gene Expressions in the Liver of the Nibbler Fish Girella punctata.
Rafiuddin MA, Matsubara H, Hatano K, Honda M, Toyota K, Kuroda K, Tsunoda K, Furusawa Y, Tabuchi Y, Hirano T, Sakatoku A, Hong CS, Srivastav AK, Amornsakun T, Shimizu N, Zanaty MI, Harumi T, Yamauchi K, Müller T, Tang N, Hattori A, Hayakawa K, Suzuki N. Rafiuddin MA, et al. Among authors: furusawa y. Toxics. 2024 Dec 18;12(12):915. doi: 10.3390/toxics12120915. Toxics. 2024. PMID: 39771130 Free PMC article.
467 results