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Dopaminergic neuron loss and up-regulation of chaperone protein mRNA induced by targeted over-expression of alpha-synuclein in mouse substantia nigra.
St Martin JL, Klucken J, Outeiro TF, Nguyen P, Keller-McGandy C, Cantuti-Castelvetri I, Grammatopoulos TN, Standaert DG, Hyman BT, McLean PJ. St Martin JL, et al. Among authors: outeiro tf. J Neurochem. 2007 Mar;100(6):1449-57. doi: 10.1111/j.1471-4159.2006.04310.x. Epub 2007 Jan 4. J Neurochem. 2007. PMID: 17241127 Free article.
Dopamine-induced conformational changes in alpha-synuclein.
Outeiro TF, Klucken J, Bercury K, Tetzlaff J, Putcha P, Oliveira LM, Quintas A, McLean PJ, Hyman BT. Outeiro TF, et al. PLoS One. 2009 Sep 4;4(9):e6906. doi: 10.1371/journal.pone.0006906. PLoS One. 2009. PMID: 19730729 Free PMC article.
β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons.
Taschenberger G, Toloe J, Tereshchenko J, Akerboom J, Wales P, Benz R, Becker S, Outeiro TF, Looger LL, Bähr M, Zweckstetter M, Kügler S. Taschenberger G, et al. Among authors: outeiro tf. Ann Neurol. 2013 Jul;74(1):109-18. doi: 10.1002/ana.23905. Epub 2013 Aug 6. Ann Neurol. 2013. PMID: 23536356
Phosphorylation modulates clearance of alpha-synuclein inclusions in a yeast model of Parkinson's disease.
Tenreiro S, Reimão-Pinto MM, Antas P, Rino J, Wawrzycka D, Macedo D, Rosado-Ramos R, Amen T, Waiss M, Magalhães F, Gomes A, Santos CN, Kaganovich D, Outeiro TF. Tenreiro S, et al. Among authors: outeiro tf. PLoS Genet. 2014 May 8;10(5):e1004302. doi: 10.1371/journal.pgen.1004302. eCollection 2014 May. PLoS Genet. 2014. PMID: 24810576 Free PMC article.
353 results