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A novel plant-produced Pfs25 fusion subunit vaccine induces long-lasting transmission blocking antibody responses.
Jones RM, Chichester JA, Manceva S, Gibbs SK, Musiychuk K, Shamloul M, Norikane J, Streatfield SJ, van de Vegte-Bolmer M, Roeffen W, Sauerwein RW, Yusibov V. Jones RM, et al. Among authors: roeffen w. Hum Vaccin Immunother. 2015;11(1):124-32. doi: 10.4161/hv.34366. Epub 2014 Nov 1. Hum Vaccin Immunother. 2015. PMID: 25483525 Free PMC article.
Antibodies to plant-produced Plasmodium falciparum sexual stage protein Pfs25 exhibit transmission blocking activity.
Farrance CE, Chichester JA, Musiychuk K, Shamloul M, Rhee A, Manceva SD, Jones RM, Mamedov T, Sharma S, Mett V, Streatfield SJ, Roeffen W, van de Vegte-Bolmer M, Sauerwein RW, Wu Y, Muratova O, Miller L, Duffy P, Sinden R, Yusibov V. Farrance CE, et al. Among authors: roeffen w. Hum Vaccin. 2011 Jan-Feb;7 Suppl:191-8. doi: 10.4161/hv.7.0.14588. Epub 2011 Jan 1. Hum Vaccin. 2011. PMID: 21266847
A plant-produced Pfs230 vaccine candidate blocks transmission of Plasmodium falciparum.
Farrance CE, Rhee A, Jones RM, Musiychuk K, Shamloul M, Sharma S, Mett V, Chichester JA, Streatfield SJ, Roeffen W, van de Vegte-Bolmer M, Sauerwein RW, Tsuboi T, Muratova OV, Wu Y, Yusibov V. Farrance CE, et al. Among authors: roeffen w. Clin Vaccine Immunol. 2011 Aug;18(8):1351-7. doi: 10.1128/CVI.05105-11. Epub 2011 Jun 29. Clin Vaccine Immunol. 2011. PMID: 21715576 Free PMC article.
A plant-produced Pfs25 VLP malaria vaccine candidate induces persistent transmission blocking antibodies against Plasmodium falciparum in immunized mice.
Jones RM, Chichester JA, Mett V, Jaje J, Tottey S, Manceva S, Casta LJ, Gibbs SK, Musiychuk K, Shamloul M, Norikane J, Mett V, Streatfield SJ, van de Vegte-Bolmer M, Roeffen W, Sauerwein RW, Yusibov V. Jones RM, et al. Among authors: roeffen w. PLoS One. 2013 Nov 18;8(11):e79538. doi: 10.1371/journal.pone.0079538. eCollection 2013. PLoS One. 2013. PMID: 24260245 Free PMC article.
Correctly folded Pfs48/45 protein of Plasmodium falciparum elicits malaria transmission-blocking immunity in mice.
Outchkourov NS, Roeffen W, Kaan A, Jansen J, Luty A, Schuiffel D, van Gemert GJ, van de Vegte-Bolmer M, Sauerwein RW, Stunnenberg HG. Outchkourov NS, et al. Among authors: roeffen w. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4301-5. doi: 10.1073/pnas.0800459105. Epub 2008 Mar 10. Proc Natl Acad Sci U S A. 2008. PMID: 18332422 Free PMC article.
Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity.
Stone WJR, Campo JJ, Ouédraogo AL, Meerstein-Kessel L, Morlais I, Da D, Cohuet A, Nsango S, Sutherland CJ, van de Vegte-Bolmer M, Siebelink-Stoter R, van Gemert GJ, Graumans W, Lanke K, Shandling AD, Pablo JV, Teng AA, Jones S, de Jong RM, Fabra-García A, Bradley J, Roeffen W, Lasonder E, Gremo G, Schwarzer E, Janse CJ, Singh SK, Theisen M, Felgner P, Marti M, Drakeley C, Sauerwein R, Bousema T, Jore MM. Stone WJR, et al. Among authors: roeffen w. Nat Commun. 2018 Feb 8;9(1):558. doi: 10.1038/s41467-017-02646-2. Nat Commun. 2018. PMID: 29422648 Free PMC article.
58 results