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Promiscuous G-protein activation by the calcium-sensing receptor.
Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu GB, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grassucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR. Zuo H, et al. Among authors: asher wb. Nature. 2024 May;629(8011):481-488. doi: 10.1038/s41586-024-07331-1. Epub 2024 Apr 17. Nature. 2024. PMID: 38632411
GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision.
Asher WB, Terry DS, Gregorio GGA, Kahsai AW, Borgia A, Xie B, Modak A, Zhu Y, Jang W, Govindaraju A, Huang LY, Inoue A, Lambert NA, Gurevich VV, Shi L, Lefkowitz RJ, Blanchard SC, Javitch JA. Asher WB, et al. Cell. 2022 May 12;185(10):1661-1675.e16. doi: 10.1016/j.cell.2022.03.042. Epub 2022 Apr 27. Cell. 2022. PMID: 35483373 Free PMC article.
Assays for detecting arrestin interaction with GPCRs.
Perry-Hauser NA, Asher WB, Hauge Pedersen M, Javitch JA. Perry-Hauser NA, et al. Among authors: asher wb. Methods Cell Biol. 2021;166:43-65. doi: 10.1016/bs.mcb.2021.06.007. Epub 2021 Jul 17. Methods Cell Biol. 2021. PMID: 34752339 Review.
Icosapent Ethyl Reduces Ischemic Events in Patients With a History of Previous Coronary Artery Bypass Grafting: REDUCE-IT CABG.
Verma S, Bhatt DL, Steg PG, Miller M, Brinton EA, Jacobson TA, Dhingra NK, Ketchum SB, Juliano RA, Jiao L, Doyle RT Jr, Granowitz C, Gibson CM, Pinto D, Giugliano RP, Budoff MJ, Mason RP, Tardif JC, Ballantyne CM; REDUCE-IT Investigators. Verma S, et al. Circulation. 2021 Dec 7;144(23):1845-1855. doi: 10.1161/CIRCULATIONAHA.121.056290. Epub 2021 Oct 28. Circulation. 2021. PMID: 34710343 Free article. Clinical Trial.
73 results