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IL-18 is not therapeutic for neovascular age-related macular degeneration.
Hirano Y, Yasuma T, Mizutani T, Fowler BJ, Tarallo V, Yasuma R, Kim Y, Bastos-Carvalho A, Kerur N, Gelfand BD, Bogdanovich S, He S, Zhang X, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Nagai H, Haro I, Núñez G, Ambati BK, Hinton DR, Ambati J. Hirano Y, et al. Among authors: nozaki m. Nat Med. 2014 Dec;20(12):1372-5. doi: 10.1038/nm.3671. Nat Med. 2014. PMID: 25473914 Free PMC article. No abstract available.
Drusen complement components C3a and C5a promote choroidal neovascularization.
Nozaki M, Raisler BJ, Sakurai E, Sarma JV, Barnum SR, Lambris JD, Chen Y, Zhang K, Ambati BK, Baffi JZ, Ambati J. Nozaki M, et al. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2328-33. doi: 10.1073/pnas.0408835103. Epub 2006 Feb 1. Proc Natl Acad Sci U S A. 2006. PMID: 16452172 Free PMC article.
1,194 results