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Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression.
Brouwers B, de Faudeur G, Osipovich AB, Goyvaerts L, Lemaire K, Boesmans L, Cauwelier EJ, Granvik M, Pruniau VP, Van Lommel L, Van Schoors J, Stancill JS, Smolders I, Goffin V, Binart N, in't Veld P, Declercq J, Magnuson MA, Creemers JW, Schuit F, Schraenen A. Brouwers B, et al. Cell Metab. 2014 Dec 2;20(6):979-90. doi: 10.1016/j.cmet.2014.11.004. Cell Metab. 2014. PMID: 25470546 Free PMC article.
mRNA expression analysis of cell cycle genes in islets of pregnant mice.
Schraenen A, de Faudeur G, Thorrez L, Lemaire K, Van Wichelen G, Granvik M, Van Lommel L, in't Veld P, Schuit F. Schraenen A, et al. Diabetologia. 2010 Dec;53(12):2579-88. doi: 10.1007/s00125-010-1912-8. Epub 2010 Oct 1. Diabetologia. 2010. PMID: 20886204 Free PMC article.
Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.
Lemaire K, Ravier MA, Schraenen A, Creemers JW, Van de Plas R, Granvik M, Van Lommel L, Waelkens E, Chimienti F, Rutter GA, Gilon P, in't Veld PA, Schuit FC. Lemaire K, et al. Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14872-7. doi: 10.1073/pnas.0906587106. Epub 2009 Aug 18. Proc Natl Acad Sci U S A. 2009. PMID: 19706465 Free PMC article.
Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in β cells.
Tornovsky-Babeay S, Dadon D, Ziv O, Tzipilevich E, Kadosh T, Schyr-Ben Haroush R, Hija A, Stolovich-Rain M, Furth-Lavi J, Granot Z, Porat S, Philipson LH, Herold KC, Bhatti TR, Stanley C, Ashcroft FM, In't Veld P, Saada A, Magnuson MA, Glaser B, Dor Y. Tornovsky-Babeay S, et al. Cell Metab. 2014 Jan 7;19(1):109-21. doi: 10.1016/j.cmet.2013.11.007. Epub 2013 Dec 12. Cell Metab. 2014. PMID: 24332968 Free article.
140 results