Yang W - Search Results

1

Design, synthesis and biological evaluation of bis-aryl ureas and amides based on 2-amino-3-purinylpyridine scaffold as DFG-out B-Raf kinase inhibitors.

Yang W, Chen Y, Zhou X, Gu Y, Qian W, Zhang F, Han W, Lu T, Tang W. Yang W, et al. Eur J Med Chem. 2015 Jan 7;89:581-96. doi: 10.1016/j.ejmech.2014.10.039. Epub 2014 Oct 16. Eur J Med Chem. 2015. PMID: 25462267

2

The discovery, design and synthesis of potent agonists of adenylyl cyclase type 2 by virtual screening combining biological evaluation.

Xu G, Yang Y, Yang Y, Song G, Li S, Zhang J, Yang W, Wang LL, Weng Z, Zuo Z. Xu G, et al. Among authors: yang w, yang y. Eur J Med Chem. 2020 Apr 1;191:112115. doi: 10.1016/j.ejmech.2020.112115. Epub 2020 Feb 5. Eur J Med Chem. 2020. PMID: 32105982

3

Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening.

Weng Z, Xu G, Chen D, Yang Y, Song G, Shen W, Zhang S, Wang L, Yang W, Zuo Z. Weng Z, et al. Among authors: yang w, yang y. Bioorg Med Chem Lett. 2020 Jan 15;30(2):126823. doi: 10.1016/j.bmcl.2019.126823. Epub 2019 Nov 16. Bioorg Med Chem Lett. 2020. PMID: 31776060

4

Scutellarin's Cardiovascular Endothelium Protective Mechanism: Important Role of PKG-Iα.

Li L, Li L, Chen C, Yang J, Li J, Hu N, Li Y, Zhang D, Guo T, Liu X, Yang W. Li L, et al. Among authors: yang w, yang j. PLoS One. 2015 Oct 6;10(10):e0139570. doi: 10.1371/journal.pone.0139570. eCollection 2015. PLoS One. 2015. PMID: 26440524 Free PMC article.

5

Isoforskolin pretreatment attenuates lipopolysaccharide-induced acute lung injury in animal models.

Yang W, Qiang D, Zhang M, Ma L, Zhang Y, Qing C, Xu Y, Zhen C, Liu J, Chen YH. Yang W, et al. Int Immunopharmacol. 2011 Jun;11(6):683-92. doi: 10.1016/j.intimp.2011.01.011. Epub 2011 Jan 25. Int Immunopharmacol. 2011. PMID: 21272678

6

Discovery of 2-(Methylcarbonylamino) thiazole as PDE4 inhibitors via virtual screening and biological evaluation.

Ma R, Song N, Wang L, Gu X, Xiong F, Zhang S, Zhang J, Yang W, Zuo Z. Ma R, et al. Among authors: yang w. J Mol Graph Model. 2023 Nov;124:108567. doi: 10.1016/j.jmgm.2023.108567. Epub 2023 Jul 14. J Mol Graph Model. 2023. PMID: 37481883

7

The hydroxamic acid derivative YPX-C-05 alleviates hypertension and vascular dysfunction through the PI3K/Akt/eNOS pathway.

Pang PP, Sun H, Yu PX, Yang WM, Zheng YT, Li X, Zheng CB. Pang PP, et al. Vascul Pharmacol. 2024 Mar;154:107251. doi: 10.1016/j.vph.2023.107251. Epub 2023 Dec 3. Vascul Pharmacol. 2024. PMID: 38052330

8

Donepezil down-regulates propionylation, 2-hydroxyisobutyrylation, butyrylation, succinylation, and crotonylation in the brain of bilateral common carotid artery occlusion-induced vascular dementia rats.

Wang H, Lu J, Gao WC, Ma X, Li N, Ding Z, Wu C, Zhu M, Qiao G, Xiao C, Zhang C, Chen C, Weng Z, Yang W, Zheng CB. Wang H, et al. Among authors: yang w. Clin Exp Pharmacol Physiol. 2020 Oct;47(10):1731-1739. doi: 10.1111/1440-1681.13352. Epub 2020 Jun 13. Clin Exp Pharmacol Physiol. 2020. PMID: 32424975

9

Isoforskolin Alleviates AECOPD by Improving Pulmonary Function and Attenuating Inflammation Which Involves Downregulation of Th17/IL-17A and NF-κB/NLRP3.

Xiao C, Cheng S, Li R, Wang Y, Zeng D, Jiang H, Liang Y, Huang R, Pan H, Wu X, Fang Y, Chen C, Li X, Zhang R, Wang X, Yang Z, Yang W. Xiao C, et al. Among authors: yang w, yang z. Front Pharmacol. 2021 Jul 30;12:721273. doi: 10.3389/fphar.2021.721273. eCollection 2021. Front Pharmacol. 2021. PMID: 34393799 Free PMC article.

10

Isoforskolin, an adenylyl cyclase activator, attenuates cigarette smoke-induced COPD in rats.

Xiao C, Cheng S, Lin H, Weng Z, Peng P, Zeng D, Du X, Zhang X, Yang Y, Liang Y, Huang R, Chen C, Wang L, Wu H, Li R, Wang X, Zhang R, Yang Z, Li X, Cao X, Yang W. Xiao C, et al. Among authors: yang w, yang y, yang z. Phytomedicine. 2021 Oct;91:153701. doi: 10.1016/j.phymed.2021.153701. Epub 2021 Aug 8. Phytomedicine. 2021. PMID: 34438230

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