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1,8-Naphthyridines IX. Potent anti-inflammatory and/or analgesic activity of a new group of substituted 5-amino[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides, of some their Mannich base derivatives and of one novel substituted 5-amino-10-oxo-10H-pyrimido[1,2-a][1,8]naphthyridine-6-carboxamide derivative.
Di Braccio M, Grossi G, Alfei S, Ballabeni V, Tognolini M, Flammini L, Giorgio C, Bertoni S, Barocelli E. Di Braccio M, et al. Eur J Med Chem. 2014 Oct 30;86:394-405. doi: 10.1016/j.ejmech.2014.08.069. Epub 2014 Aug 27. Eur J Med Chem. 2014. PMID: 25194932
1,8-Naphthyridines VII. New substituted 5-amino[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides and their isosteric analogues, exhibiting notable anti-inflammatory and/or analgesic activities, but no acute gastrolesivity.
Roma G, Grossi G, Di Braccio M, Piras D, Ballabeni V, Tognolini M, Bertoni S, Barocelli E. Roma G, et al. Among authors: di braccio m. Eur J Med Chem. 2008 Aug;43(8):1665-80. doi: 10.1016/j.ejmech.2007.10.010. Epub 2007 Oct 11. Eur J Med Chem. 2008. PMID: 18045747
1,8-Naphthyridines VIII. Novel 5-aminoimidazo[1,2-a] [1,8]naphthyridine-6-carboxamide and 5-amino[1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6-carboxamide derivatives showing potent analgesic or anti-inflammatory activity, respectively, and completely devoid of acute gastrolesivity.
Roma G, Di Braccio M, Grossi G, Piras D, Ballabeni V, Tognolini M, Bertoni S, Barocelli E. Roma G, et al. Among authors: di braccio m. Eur J Med Chem. 2010 Jan;45(1):352-66. doi: 10.1016/j.ejmech.2009.10.020. Epub 2009 Nov 13. Eur J Med Chem. 2010. PMID: 19913952
1,5-benzodiazepines. Part XIII. Substituted 4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5-amines and 4H-imidazo[1,2-a][1,5]benzodiazepin-5-amines as analgesic, anti-inflammatory and/or antipyretic agents with low acute toxicity.
Grossi G, Di Braccio M, Roma G, Ballabeni V, Tognolini M, Calcina F, Barocelli E. Grossi G, et al. Among authors: di braccio m. Eur J Med Chem. 2002 Dec;37(12):933-44. doi: 10.1016/s0223-5234(02)01400-9. Eur J Med Chem. 2002. PMID: 12660018
40 results