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p19 INK4d controls hematopoietic stem cells in a cell-autonomous manner during genotoxic stress and through the microenvironment during aging.
Hilpert M, Legrand C, Bluteau D, Balayn N, Betems A, Bluteau O, Villeval JL, Louache F, Gonin P, Debili N, Plo I, Vainchenker W, Gilles L, Raslova H. Hilpert M, et al. Among authors: betems a. Stem Cell Reports. 2014 Dec 9;3(6):1085-102. doi: 10.1016/j.stemcr.2014.10.005. Epub 2014 Nov 20. Stem Cell Reports. 2014. PMID: 25458892 Free PMC article.
CXCR4 inhibitors selectively eliminate CXCR4-expressing human acute myeloid leukemia cells in NOG mouse model.
Zhang Y, Patel S, Abdelouahab H, Wittner M, Willekens C, Shen S, Betems A, Joulin V, Opolon P, Bawa O, Pasquier F, Ito M, Fujii N, Gonin P, Solary E, Vainchenker W, Coppo P, De Botton S, Louache F. Zhang Y, et al. Among authors: betems a. Cell Death Dis. 2012 Oct 4;3(10):e396. doi: 10.1038/cddis.2012.137. Cell Death Dis. 2012. PMID: 23034331 Free PMC article.
Genetic hierarchy and temporal variegation in the clonal history of acute myeloid leukaemia.
Hirsch P, Zhang Y, Tang R, Joulin V, Boutroux H, Pronier E, Moatti H, Flandrin P, Marzac C, Bories D, Fava F, Mokrani H, Betems A, Lorre F, Favier R, Féger F, Mohty M, Douay L, Legrand O, Bilhou-Nabera C, Louache F, Delhommeau F. Hirsch P, et al. Among authors: betems a. Nat Commun. 2016 Aug 18;7:12475. doi: 10.1038/ncomms12475. Nat Commun. 2016. PMID: 27534895 Free PMC article.