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Kinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivo.
Schuhwerk H, Bruhn C, Siniuk K, Min W, Erener S, Grigaravicius P, Krüger A, Ferrari E, Zubel T, Lazaro D, Monajembashi S, Kiesow K, Kroll T, Bürkle A, Mangerich A, Hottiger M, Wang ZQ. Schuhwerk H, et al. Among authors: kroll t. Nucleic Acids Res. 2017 Nov 2;45(19):11174-11192. doi: 10.1093/nar/gkx717. Nucleic Acids Res. 2017. PMID: 28977496 Free PMC article.
Cell Type-Specific Role of RNA Nuclease SMG6 in Neurogenesis.
Guerra GM, May D, Kroll T, Koch P, Groth M, Wang ZQ, Li TL, Grigaravičius P. Guerra GM, et al. Among authors: kroll t. Cells. 2021 Nov 30;10(12):3365. doi: 10.3390/cells10123365. Cells. 2021. PMID: 34943873 Free PMC article.
HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development.
Connell M, Chen H, Jiang J, Kuan CW, Fotovati A, Chu TL, He Z, Lengyell TC, Li H, Kroll T, Li AM, Goldowitz D, Frappart L, Ploubidou A, Patel MS, Pilarski LM, Simpson EM, Lange PF, Allan DW, Maxwell CA. Connell M, et al. Among authors: kroll t. Elife. 2017 Oct 10;6:e28672. doi: 10.7554/eLife.28672. Elife. 2017. PMID: 28994651 Free PMC article.
The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response.
Schuhwerk H, Kleemann J, Gupta P, van Roey R, Armstark I, Kreileder M, Feldker N, Ramesh V, Hajjaj Y, Fuchs K, Mahapatro M, Hribersek M, Volante M, Groenewoud A, Engel FB, Ceppi P, Eckstein M, Hartmann A, Müller F, Kroll T, Stemmler MP, Brabletz S, Brabletz T. Schuhwerk H, et al. Among authors: kroll t. Cell Rep. 2022 Dec 13;41(11):111819. doi: 10.1016/j.celrep.2022.111819. Cell Rep. 2022. PMID: 36516781 Free article.
403 results