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Inflammatory cytokines epigenetically regulate rheumatoid arthritis fibroblast-like synoviocyte activation by suppressing HDAC5 expression.
Angiolilli C, Grabiec AM, Ferguson BS, Ospelt C, Malvar Fernandez B, van Es IE, van Baarsen LG, Gay S, McKinsey TA, Tak PP, Baeten DL, Reedquist KA. Angiolilli C, et al. Among authors: baeten dl. Ann Rheum Dis. 2016 Feb;75(2):430-8. doi: 10.1136/annrheumdis-2014-205635. Epub 2014 Dec 1. Ann Rheum Dis. 2016. PMID: 25452308 Free PMC article.
Synovial tissue analysis in clinical trials.
Bresnihan B, Baeten D, Firestein GS, Fitzgerald OM, Gerlag DM, Haringman JJ, McInnes IB, Reece RJ, Smith MD, Ulfgren AK, Veale DJ, Tak PP; OMERACT 7 Special Interest Group. Bresnihan B, et al. J Rheumatol. 2005 Dec;32(12):2481-4. J Rheumatol. 2005. PMID: 16331792 Review.
Synovial inflammation does not change in the absence of effective treatment: implications for the use of synovial histopathology as biomarker in early phase clinical trials in rheumatoid arthritis.
Baeten D, Houbiers J, Kruithof E, Vandooren B, Van den Bosch F, Boots AM, Veys EM, Miltenburg AM, De Keyser F. Baeten D, et al. Ann Rheum Dis. 2006 Aug;65(8):990-7. doi: 10.1136/ard.2005.047852. Epub 2006 Jan 13. Ann Rheum Dis. 2006. PMID: 16414969 Free PMC article.
280 results