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Page 1
Systematic evaluation of non-animal test methods for skin sensitisation safety assessment.
Reisinger K, Hoffmann S, Alépée N, Ashikaga T, Barroso J, Elcombe C, Gellatly N, Galbiati V, Gibbs S, Groux H, Hibatallah J, Keller D, Kern P, Klaric M, Kolle S, Kuehnl J, Lambrechts N, Lindstedt M, Millet M, Martinozzi-Teissier S, Natsch A, Petersohn D, Pike I, Sakaguchi H, Schepky A, Tailhardat M, Templier M, van Vliet E, Maxwell G. Reisinger K, et al. Among authors: schepky a. Toxicol In Vitro. 2015 Feb;29(1):259-70. doi: 10.1016/j.tiv.2014.10.018. Toxicol In Vitro. 2015. PMID: 25448812 Free article.
Suitability of different reconstructed human skin models in the skin and liver Chip2 microphysiological model to investigate the kinetics and first-pass skin metabolism of the hair dye, 4-amino-2-hydroxytoluene.
Brandmair K, Tao TP, Gerlach S, Przibilla J, Schepky A, Marx U, Hewitt NJ, Kühnl J, Maschmeyer I. Brandmair K, et al. Among authors: schepky a. J Appl Toxicol. 2024 Mar;44(3):333-343. doi: 10.1002/jat.4542. Epub 2023 Sep 12. J Appl Toxicol. 2024. PMID: 37699698 Free article.
Identification of dihydromyricetin as a natural DNA methylation inhibitor with rejuvenating activity in human skin.
Falckenhayn C, Bienkowska A, Söhle J, Wegner K, Raddatz G, Kristof B, Kuck D, Siegner R, Kaufmann R, Korn J, Baumann S, Lange D, Schepky A, Völzke H, Kaderali L, Winnefeld M, Lyko F, Grönniger E. Falckenhayn C, et al. Among authors: schepky a. Front Aging. 2024 Mar 4;4:1258184. doi: 10.3389/fragi.2023.1258184. eCollection 2023. Front Aging. 2024. PMID: 38500495 Free PMC article.
A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: genotoxicity. A COLIPA analysis.
Pfuhler S, Kirst A, Aardema M, Banduhn N, Goebel C, Araki D, Costabel-Farkas M, Dufour E, Fautz R, Harvey J, Hewitt NJ, Hibatallah J, Carmichael P, Macfarlane M, Reisinger K, Rowland J, Schellauf F, Schepky A, Scheel J. Pfuhler S, et al. Among authors: schepky a. Regul Toxicol Pharmacol. 2010 Jul-Aug;57(2-3):315-24. doi: 10.1016/j.yrtph.2010.03.012. Epub 2010 Apr 9. Regul Toxicol Pharmacol. 2010. PMID: 20382194 Free article.
Identifying and characterizing chemical skin sensitizers without animal testing: Colipa's research and method development program.
Aeby P, Ashikaga T, Bessou-Touya S, Schepky A, Gerberick F, Kern P, Marrec-Fairley M, Maxwell G, Ovigne JM, Sakaguchi H, Reisinger K, Tailhardat M, Martinozzi-Teissier S, Winkler P. Aeby P, et al. Among authors: schepky a. Toxicol In Vitro. 2010 Sep;24(6):1465-73. doi: 10.1016/j.tiv.2010.07.005. Epub 2010 Jul 17. Toxicol In Vitro. 2010. PMID: 20624454 Review.
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing.
Basketter DA, Clewell H, Kimber I, Rossi A, Blaauboer B, Burrier R, Daneshian M, Eskes C, Goldberg A, Hasiwa N, Hoffmann S, Jaworska J, Knudsen TB, Landsiedel R, Leist M, Locke P, Maxwell G, McKim J, McVey EA, Ouédraogo G, Patlewicz G, Pelkonen O, Roggen E, Rovida C, Ruhdel I, Schwarz M, Schepky A, Schoeters G, Skinner N, Trentz K, Turner M, Vanparys P, Yager J, Zurlo J, Hartung T. Basketter DA, et al. Among authors: schepky a. ALTEX. 2012;29(1):3-91. doi: 10.14573/altex.2012.1.003. ALTEX. 2012. PMID: 22307314
Guiding principles for the implementation of non-animal safety assessment approaches for cosmetics: skin sensitisation.
Goebel C, Aeby P, Ade N, Alépée N, Aptula A, Araki D, Dufour E, Gilmour N, Hibatallah J, Keller D, Kern P, Kirst A, Marrec-Fairley M, Maxwell G, Rowland J, Safford B, Schellauf F, Schepky A, Seaman C, Teichert T, Tessier N, Teissier S, Weltzien HU, Winkler P, Scheel J. Goebel C, et al. Among authors: schepky a. Regul Toxicol Pharmacol. 2012 Jun;63(1):40-52. doi: 10.1016/j.yrtph.2012.02.007. Epub 2012 Feb 21. Regul Toxicol Pharmacol. 2012. PMID: 22374415 Free article.
64 results