Zasadil LM - Search Results

1

A Golgi-localized pool of the mitotic checkpoint component Mad1 controls integrin secretion and cell migration.

Wan J, Zhu F, Zasadil LM, Yu J, Wang L, Johnson A, Berthier E, Beebe DJ, Audhya A, Weaver BA. Wan J, et al. Among authors: zasadil lm. Curr Biol. 2014 Nov 17;24(22):2687-92. doi: 10.1016/j.cub.2014.09.052. Epub 2014 Oct 23. Curr Biol. 2014. PMID: 25447996 Free PMC article.

2

Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons.

Ryan SD, Britigan EM, Zasadil LM, Witte K, Audhya A, Roopra A, Weaver BA. Ryan SD, et al. Among authors: zasadil lm. Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):E2205-14. doi: 10.1073/pnas.1201911109. Epub 2012 Jul 9. Proc Natl Acad Sci U S A. 2012. PMID: 22778409 Free PMC article.

3

The ARF tumor suppressor prevents chromosomal instability and ensures mitotic checkpoint fidelity through regulation of Aurora B.

Britigan EM, Wan J, Zasadil LM, Ryan SD, Weaver BA. Britigan EM, et al. Among authors: zasadil lm. Mol Biol Cell. 2014 Sep 15;25(18):2761-73. doi: 10.1091/mbc.E14-05-0966. Epub 2014 Jul 23. Mol Biol Cell. 2014. PMID: 25057018 Free PMC article.

4

2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells.

Zasadil LM, Britigan EM, Weaver BA. Zasadil LM, et al. Semin Cell Dev Biol. 2013 Apr;24(4):370-9. doi: 10.1016/j.semcdb.2013.02.001. Epub 2013 Feb 13. Semin Cell Dev Biol. 2013. PMID: 23416057 Free PMC article.

5

High rates of chromosome missegregation suppress tumor progression but do not inhibit tumor initiation.

Zasadil LM, Britigan EM, Ryan SD, Kaur C, Guckenberger DJ, Beebe DJ, Moser AR, Weaver BA. Zasadil LM, et al. Mol Biol Cell. 2016 Jul 1;27(13):1981-9. doi: 10.1091/mbc.E15-10-0747. Epub 2016 May 4. Mol Biol Cell. 2016. PMID: 27146113 Free PMC article.

6

Living in CIN: Mitotic Infidelity and Its Consequences for Tumor Promotion and Suppression.

Funk LC, Zasadil LM, Weaver BA. Funk LC, et al. Among authors: zasadil lm. Dev Cell. 2016 Dec 19;39(6):638-652. doi: 10.1016/j.devcel.2016.10.023. Dev Cell. 2016. PMID: 27997823 Free PMC article. Review.

7

Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors.

Silk AD, Zasadil LM, Holland AJ, Vitre B, Cleveland DW, Weaver BA. Silk AD, et al. Among authors: zasadil lm. Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):E4134-41. doi: 10.1073/pnas.1317042110. Epub 2013 Oct 16. Proc Natl Acad Sci U S A. 2013. PMID: 24133140 Free PMC article.

8

Cytotoxicity of paclitaxel in breast cancer is due to chromosome missegregation on multipolar spindles.

Zasadil LM, Andersen KA, Yeum D, Rocque GB, Wilke LG, Tevaarwerk AJ, Raines RT, Burkard ME, Weaver BA. Zasadil LM, et al. Sci Transl Med. 2014 Mar 26;6(229):229ra43. doi: 10.1126/scitranslmed.3007965. Sci Transl Med. 2014. PMID: 24670687 Free PMC article.

9

High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instability.

Matson DR, Denu RA, Zasadil LM, Burkard ME, Weaver BA, Flynn C, Stukenberg PT. Matson DR, et al. Among authors: zasadil lm. BMC Cancer. 2021 Feb 23;21(1):186. doi: 10.1186/s12885-021-07893-7. BMC Cancer. 2021. PMID: 33622270 Free PMC article.

10

Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer.

Denu RA, Zasadil LM, Kanugh C, Laffin J, Weaver BA, Burkard ME. Denu RA, et al. Among authors: zasadil lm. BMC Cancer. 2016 Jan 29;16:47. doi: 10.1186/s12885-016-2083-x. BMC Cancer. 2016. PMID: 26832928 Free PMC article.

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