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A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome.
Scheibye-Knudsen M, Mitchell SJ, Fang EF, Iyama T, Ward T, Wang J, Dunn CA, Singh N, Veith S, Hasan-Olive MM, Mangerich A, Wilson MA, Mattson MP, Bergersen LH, Cogger VC, Warren A, Le Couteur DG, Moaddel R, Wilson DM 3rd, Croteau DL, de Cabo R, Bohr VA. Scheibye-Knudsen M, et al. Among authors: dunn ca. Cell Metab. 2014 Nov 4;20(5):840-855. doi: 10.1016/j.cmet.2014.10.005. Epub 2014 Nov 4. Cell Metab. 2014. PMID: 25440059 Free PMC article.
Sporadic Alzheimer disease fibroblasts display an oxidative stress phenotype.
Ramamoorthy M, Sykora P, Scheibye-Knudsen M, Dunn C, Kasmer C, Zhang Y, Becker KG, Croteau DL, Bohr VA. Ramamoorthy M, et al. Free Radic Biol Med. 2012 Sep 15;53(6):1371-80. doi: 10.1016/j.freeradbiomed.2012.07.018. Epub 2012 Aug 3. Free Radic Biol Med. 2012. PMID: 22885031 Free PMC article.
RAPADILINO RECQL4 mutant protein lacks helicase and ATPase activity.
Croteau DL, Rossi ML, Ross J, Dawut L, Dunn C, Kulikowicz T, Bohr VA. Croteau DL, et al. Biochim Biophys Acta. 2012 Nov;1822(11):1727-34. doi: 10.1016/j.bbadis.2012.07.014. Epub 2012 Jul 31. Biochim Biophys Acta. 2012. PMID: 22885111 Free PMC article.
Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging.
Occean JR, Yang N, Sun Y, Dawkins MS, Munk R, Belair C, Dar S, Anerillas C, Wang L, Shi C, Dunn C, Bernier M, Price NL, Kim JS, Cui CY, Fan J, Bhattacharyya M, De S, Maragkakis M, deCabo R, Sidoli S, Sen P. Occean JR, et al. bioRxiv [Preprint]. 2024 Jul 3:2023.02.15.528714. doi: 10.1101/2023.02.15.528714. bioRxiv. 2024. Update in: Nat Commun. 2024 Jul 28;15(1):6357. doi: 10.1038/s41467-024-50725-y PMID: 36824863 Free PMC article. Updated. Preprint.
72 results