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Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma.
Hackett CS, Quigley DA, Wong RA, Chen J, Cheng C, Song YK, Wei JS, Pawlikowska L, Bao Y, Goldenberg DD, Nguyen K, Gustafson WC, Rallapalli SK, Cho YJ, Cook JM, Kozlov S, Mao JH, Van Dyke T, Kwok PY, Khan J, Balmain A, Fan Q, Weiss WA. Hackett CS, et al. Among authors: cook jm. Cell Rep. 2014 Nov 6;9(3):1034-46. doi: 10.1016/j.celrep.2014.09.046. Epub 2014 Oct 23. Cell Rep. 2014. PMID: 25437558 Free PMC article.
A study of the structure-activity relationship of GABA(A)-benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis.
Han D, Holger Försterling F, Li X, Deschamps JR, Parrish D, Cao H, Rallapalli S, Clayton T, Teng Y, Majumder S, Sankar S, Roth BL, Sieghart W, Furtmuller R, Rowlett JK, Weed MR, Cook JM. Han D, et al. Among authors: cook jm. Bioorg Med Chem. 2008 Oct 1;16(19):8853-62. doi: 10.1016/j.bmc.2008.08.072. Epub 2008 Sep 2. Bioorg Med Chem. 2008. PMID: 18790643 Free PMC article.
Recent progress in the total synthesis of indole alkaloids.
Edwankar CR, Edwankar RV, Namjoshi OA, Rallapalli SK, Yang J, Cook JM. Edwankar CR, et al. Among authors: cook jm. Curr Opin Drug Discov Devel. 2009 Nov;12(6):752-71. Curr Opin Drug Discov Devel. 2009. PMID: 19894188 Review.
Insights into functional pharmacology of α₁ GABA(A) receptors: how much does partial activation at the benzodiazepine site matter?
Joksimović S, Varagic Z, Kovačević J, Van Linn M, Milić M, Rallapalli S, Timić T, Sieghart W, Cook JM, Savić MM. Joksimović S, et al. Among authors: cook jm. Psychopharmacology (Berl). 2013 Nov;230(1):113-23. doi: 10.1007/s00213-013-3143-4. Epub 2013 May 18. Psychopharmacology (Berl). 2013. PMID: 23685860 Free PMC article.
628 results