Schöneich C - Search Results

1

Do not drop: mechanical shock in vials causes cavitation, protein aggregation, and particle formation.

Randolph TW, Schiltz E, Sederstrom D, Steinmann D, Mozziconacci O, Schöneich C, Freund E, Ricci MS, Carpenter JF, Lengsfeld CS. Randolph TW, et al. Among authors: schoneich c. J Pharm Sci. 2015 Feb;104(2):602-11. doi: 10.1002/jps.24259. Epub 2014 Nov 21. J Pharm Sci. 2015. PMID: 25418950 Free PMC article.

2

Reversible intramolecular hydrogen transfer between protein cysteine thiyl radicals and alpha C-H bonds in insulin: control of selectivity by secondary structure.

Mozziconacci O, Williams TD, Kerwin BA, Schöneich C. Mozziconacci O, et al. Among authors: schoneich c. J Phys Chem B. 2008 Dec 11;112(49):15921-32. doi: 10.1021/jp8066519. J Phys Chem B. 2008. PMID: 19368019

3

Light-induced aggregation of type I soluble tumor necrosis factor receptor.

Roy S, Mason BD, Schöneich CS, Carpenter JF, Boone TC, Kerwin BA. Roy S, et al. Among authors: schoneich cs. J Pharm Sci. 2009 Sep;98(9):3182-99. doi: 10.1002/jps.21750. J Pharm Sci. 2009. PMID: 19384921

4

Photolysis of an intrachain peptide disulfide bond: primary and secondary processes, formation of H2S, and hydrogen transfer reactions.

Mozziconacci O, Kerwin BA, Schöneich C. Mozziconacci O, et al. Among authors: schoneich c. J Phys Chem B. 2010 Mar 18;114(10):3668-88. doi: 10.1021/jp910789x. J Phys Chem B. 2010. PMID: 20178349

5

Reversible hydrogen transfer between cysteine thiyl radical and glycine and alanine in model peptides: covalent H/D exchange, radical-radical reactions, and L- to D-Ala conversion.

Mozziconacci O, Kerwin BA, Schöneich C. Mozziconacci O, et al. Among authors: schoneich c. J Phys Chem B. 2010 May 20;114(19):6751-62. doi: 10.1021/jp101508b. J Phys Chem B. 2010. PMID: 20415493

6

Exposure of a monoclonal antibody, IgG1, to UV-light leads to protein dithiohemiacetal and thioether cross-links: a role for thiyl radicals?

Mozziconacci O, Kerwin BA, Schöneich C. Mozziconacci O, et al. Among authors: schoneich c. Chem Res Toxicol. 2010 Aug 16;23(8):1310-2. doi: 10.1021/tx100193b. Chem Res Toxicol. 2010. PMID: 20604533

7

Photolysis of recombinant human insulin in the solid state: formation of a dithiohemiacetal product at the C-terminal disulfide bond.

Mozziconacci O, Haywood J, Gorman EM, Munson E, Schöneich C. Mozziconacci O, et al. Among authors: schoneich c. Pharm Res. 2012 Jan;29(1):121-33. doi: 10.1007/s11095-011-0519-1. Epub 2011 Jul 12. Pharm Res. 2012. PMID: 21748537

8

Reversible hydrogen transfer reactions of cysteine thiyl radicals in peptides: the conversion of cysteine into dehydroalanine and alanine, and of alanine into dehydroalanine.

Mozziconacci O, Kerwin BA, Schöneich C. Mozziconacci O, et al. Among authors: schoneich c. J Phys Chem B. 2011 Oct 27;115(42):12287-305. doi: 10.1021/jp2070453. Epub 2011 Sep 30. J Phys Chem B. 2011. PMID: 21895001 Free PMC article.

9

Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release.

Jiskoot W, Randolph TW, Volkin DB, Middaugh CR, Schöneich C, Winter G, Friess W, Crommelin DJ, Carpenter JF. Jiskoot W, et al. Among authors: schoneich c. J Pharm Sci. 2012 Mar;101(3):946-54. doi: 10.1002/jps.23018. Epub 2011 Dec 14. J Pharm Sci. 2012. PMID: 22170395

10

Oxidation of human growth hormone by oxygen-centered radicals: formation of Leu-101 hydroperoxide and Tyr-103 oxidation products.

Steinmann D, Ji JA, Wang YJ, Schöneich C. Steinmann D, et al. Among authors: schoneich c. Mol Pharm. 2012 Apr 2;9(4):803-14. doi: 10.1021/mp3001028. Epub 2012 Mar 21. Mol Pharm. 2012. PMID: 22397317

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