Giorgis M - Search Results

1

Electrophilic warhead-based design of compounds preventing NLRP3 inflammasome-dependent pyroptosis.

Cocco M, Garella D, Di Stilo A, Borretto E, Stevanato L, Giorgis M, Marini E, Fantozzi R, Miglio G, Bertinaria M. Cocco M, et al. Among authors: giorgis m. J Med Chem. 2014 Dec 26;57(24):10366-82. doi: 10.1021/jm501072b. Epub 2014 Dec 4. J Med Chem. 2014. PMID: 25418070 Free article.

2

NO-donor phenols: a new class of products endowed with antioxidant and vasodilator properties.

Boschi D, Tron GC, Lazzarato L, Chegaev K, Cena C, Di Stilo A, Giorgis M, Bertinaria M, Fruttero R, Gasco A. Boschi D, et al. Among authors: giorgis m. J Med Chem. 2006 May 18;49(10):2886-97. doi: 10.1021/jm0510530. J Med Chem. 2006. PMID: 16686532

3

Novel antioxidant agents deriving from molecular combination of Vitamin C and NO-donor moieties.

Cena C, Chegaev K, Balbo S, Lazzarato L, Rolando B, Giorgis M, Marini E, Fruttero R, Gasco A. Cena C, et al. Among authors: giorgis m. Bioorg Med Chem. 2008 May 1;16(9):5199-206. doi: 10.1016/j.bmc.2008.03.014. Epub 2008 Mar 6. Bioorg Med Chem. 2008. PMID: 18359636

4

Edaravone derivatives containing NO-donor functions.

Chegaev K, Cena C, Giorgis M, Rolando B, Tosco P, Bertinaria M, Fruttero R, Carrupt PA, Gasco A. Chegaev K, et al. Among authors: giorgis m. J Med Chem. 2009 Jan 22;52(2):574-8. doi: 10.1021/jm8007008. J Med Chem. 2009. PMID: 19113954 Free article.

5

Multitarget drugs: synthesis and preliminary pharmacological characterization of zileuton analogues endowed with Dual 5-LO inhibitor and NO-dependent activities.

Boschi D, Giorgis M, Cena C, Talniya NC, Di Stilo A, Morini G, Coruzzi G, Guaita E, Fruttero R, Gasco A. Boschi D, et al. Among authors: giorgis m. ChemMedChem. 2010 Sep 3;5(9):1444-9. doi: 10.1002/cmdc.201000198. ChemMedChem. 2010. PMID: 20645382 Free article. No abstract available.

6

1,2,5-Oxadiazole analogues of leflunomide and related compounds.

Giorgis M, Lolli ML, Rolando B, Rao A, Tosco P, Chaurasia S, Marabello D, Fruttero R, Gasco A. Giorgis M, et al. Eur J Med Chem. 2011 Jan;46(1):383-92. doi: 10.1016/j.ejmech.2010.10.029. Epub 2010 Nov 3. Eur J Med Chem. 2011. PMID: 21109332

7

Synthesis, physicochemical characterization, and biological activities of new carnosine derivatives stable in human serum as potential neuroprotective agents.

Bertinaria M, Rolando B, Giorgis M, Montanaro G, Guglielmo S, Buonsanti MF, Carabelli V, Gavello D, Daniele PG, Fruttero R, Gasco A. Bertinaria M, et al. Among authors: giorgis m. J Med Chem. 2011 Jan 27;54(2):611-21. doi: 10.1021/jm101394n. Epub 2010 Dec 23. J Med Chem. 2011. PMID: 21182325

8

Amodiaquine analogues containing NO-donor substructures: synthesis and their preliminary evaluation as potential tools in the treatment of cerebral malaria.

Bertinaria M, Guglielmo S, Rolando B, Giorgis M, Aragno C, Fruttero R, Gasco A, Parapini S, Taramelli D, Martins YC, Carvalho LJ. Bertinaria M, et al. Among authors: giorgis m. Eur J Med Chem. 2011 May;46(5):1757-67. doi: 10.1016/j.ejmech.2011.02.029. Epub 2011 Feb 22. Eur J Med Chem. 2011. PMID: 21396743

9

Synthesis physicochemical profile and PAMPA study of new NO-donor edaravone co-drugs.

Rolando B, Filieri A, Chegaev K, Lazzarato L, Giorgis M, De Nardi C, Fruttero R, Martel S, Carrupt PA, Gasco A. Rolando B, et al. Among authors: giorgis m. Bioorg Med Chem. 2012 Jan 15;20(2):841-50. doi: 10.1016/j.bmc.2011.11.065. Epub 2011 Dec 8. Bioorg Med Chem. 2012. PMID: 22222158 Free article.

10

New inhibitors of dihydroorotate dehydrogenase (DHODH) based on the 4-hydroxy-1,2,5-oxadiazol-3-yl (hydroxyfurazanyl) scaffold.

Lolli ML, Giorgis M, Tosco P, Foti A, Fruttero R, Gasco A. Lolli ML, et al. Among authors: giorgis m. Eur J Med Chem. 2012 Mar;49:102-9. doi: 10.1016/j.ejmech.2011.12.038. Epub 2012 Jan 3. Eur J Med Chem. 2012. PMID: 22245049 Free article.

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