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Peripheral α-defensins 1 and 2 are elevated in Alzheimer's disease.
Watt AD, Perez KA, Ang CS, O'Donnell P, Rembach A, Pertile KK, Rumble RL, Trounson BO, Fowler CJ, Faux NG, Masters CL, Villemagne VL, Barnham KJ. Watt AD, et al. Among authors: perez ka. J Alzheimers Dis. 2015;44(4):1131-43. doi: 10.3233/JAD-142286. J Alzheimers Dis. 2015. PMID: 25408207
In vitro characterization of Pittsburgh compound-B binding to Lewy bodies.
Fodero-Tavoletti MT, Smith DP, McLean CA, Adlard PA, Barnham KJ, Foster LE, Leone L, Perez K, Cortés M, Culvenor JG, Li QX, Laughton KM, Rowe CC, Masters CL, Cappai R, Villemagne VL. Fodero-Tavoletti MT, et al. J Neurosci. 2007 Sep 26;27(39):10365-71. doi: 10.1523/JNEUROSCI.0630-07.2007. J Neurosci. 2007. PMID: 17898208 Free PMC article.
Platinum-based inhibitors of amyloid-beta as therapeutic agents for Alzheimer's disease.
Barnham KJ, Kenche VB, Ciccotosto GD, Smith DP, Tew DJ, Liu X, Perez K, Cranston GA, Johanssen TJ, Volitakis I, Bush AI, Masters CL, White AR, Smith JP, Cherny RA, Cappai R. Barnham KJ, et al. Proc Natl Acad Sci U S A. 2008 May 13;105(19):6813-8. doi: 10.1073/pnas.0800712105. Epub 2008 May 7. Proc Natl Acad Sci U S A. 2008. PMID: 18463291 Free PMC article.
Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta.
Adlard PA, Cherny RA, Finkelstein DI, Gautier E, Robb E, Cortes M, Volitakis I, Liu X, Smith JP, Perez K, Laughton K, Li QX, Charman SA, Nicolazzo JA, Wilkins S, Deleva K, Lynch T, Kok G, Ritchie CW, Tanzi RE, Cappai R, Masters CL, Barnham KJ, Bush AI. Adlard PA, et al. Neuron. 2008 Jul 10;59(1):43-55. doi: 10.1016/j.neuron.2008.06.018. Neuron. 2008. PMID: 18614028 Free article.
Increasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation.
Crouch PJ, Hung LW, Adlard PA, Cortes M, Lal V, Filiz G, Perez KA, Nurjono M, Caragounis A, Du T, Laughton K, Volitakis I, Bush AI, Li QX, Masters CL, Cappai R, Cherny RA, Donnelly PS, White AR, Barnham KJ. Crouch PJ, et al. Among authors: perez ka. Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):381-6. doi: 10.1073/pnas.0809057106. Epub 2009 Jan 2. Proc Natl Acad Sci U S A. 2009. PMID: 19122148 Free PMC article.
Restored degradation of the Alzheimer's amyloid-beta peptide by targeting amyloid formation.
Crouch PJ, Tew DJ, Du T, Nguyen DN, Caragounis A, Filiz G, Blake RE, Trounce IA, Soon CP, Laughton K, Perez KA, Li QX, Cherny RA, Masters CL, Barnham KJ, White AR. Crouch PJ, et al. Among authors: perez ka. J Neurochem. 2009 Mar;108(5):1198-207. doi: 10.1111/j.1471-4159.2009.05870.x. Epub 2009 Jan 7. J Neurochem. 2009. PMID: 19141082 Free article.
61 results