Barham WJ - Search Results

1

Biocompatible mannosylated endosomal-escape nanoparticles enhance selective delivery of short nucleotide sequences to tumor associated macrophages.

Ortega RA, Barham WJ, Kumar B, Tikhomirov O, McFadden ID, Yull FE, Giorgio TD. Ortega RA, et al. Among authors: barham wj. Nanoscale. 2015 Jan 14;7(2):500-10. doi: 10.1039/c4nr03962a. Nanoscale. 2015. PMID: 25408159

2

Macrophage-specific RNA interference targeting via "click", mannosylated polymeric micelles.

Yu SS, Lau CM, Barham WJ, Onishko HM, Nelson CE, Li H, Smith CA, Yull FE, Duvall CL, Giorgio TD. Yu SS, et al. Among authors: barham wj. Mol Pharm. 2013 Mar 4;10(3):975-87. doi: 10.1021/mp300434e. Epub 2013 Feb 12. Mol Pharm. 2013. PMID: 23331322 Free PMC article.

3

Manipulating the NF-κB pathway in macrophages using mannosylated, siRNA-delivering nanoparticles can induce immunostimulatory and tumor cytotoxic functions.

Ortega RA, Barham W, Sharman K, Tikhomirov O, Giorgio TD, Yull FE. Ortega RA, et al. Int J Nanomedicine. 2016 May 18;11:2163-77. doi: 10.2147/IJN.S93483. eCollection 2016. Int J Nanomedicine. 2016. PMID: 27274241 Free PMC article.

4

Microenvironmental effects limit efficacy of thymoquinone treatment in a mouse model of ovarian cancer.

Wilson AJ, Saskowski J, Barham W, Khabele D, Yull F. Wilson AJ, et al. Mol Cancer. 2015 Nov 9;14:192. doi: 10.1186/s12943-015-0463-5. Mol Cancer. 2015. PMID: 26552746 Free PMC article.

5

Increased canonical NF-kappaB signaling specifically in macrophages is sufficient to limit tumor progression in syngeneic murine models of ovarian cancer.

Hoover AA, Hufnagel DH, Harris W, Bullock K, Glass EB, Liu E, Barham W, Crispens MA, Khabele D, Giorgio TD, Wilson AJ, Yull FE. Hoover AA, et al. BMC Cancer. 2020 Oct 7;20(1):970. doi: 10.1186/s12885-020-07450-8. BMC Cancer. 2020. PMID: 33028251 Free PMC article.

6

NF-κB signaling in fetal lung macrophages disrupts airway morphogenesis.

Blackwell TS, Hipps AN, Yamamoto Y, Han W, Barham WJ, Ostrowski MC, Yull FE, Prince LS. Blackwell TS, et al. Among authors: barham wj. J Immunol. 2011 Sep 1;187(5):2740-7. doi: 10.4049/jimmunol.1101495. Epub 2011 Jul 20. J Immunol. 2011. PMID: 21775686 Free PMC article.

7

Inhibition of NF-kappa B activity in mammary epithelium increases tumor latency and decreases tumor burden.

Connelly L, Barham W, Onishko HM, Sherrill T, Chodosh LA, Blackwell TS, Yull FE. Connelly L, et al. Oncogene. 2011 Mar 24;30(12):1402-12. doi: 10.1038/onc.2010.521. Epub 2010 Nov 15. Oncogene. 2011. PMID: 21076466 Free PMC article.

8

NF-kappaB activation within macrophages leads to an anti-tumor phenotype in a mammary tumor lung metastasis model.

Connelly L, Barham W, Onishko HM, Chen L, Sherrill TP, Zabuawala T, Ostrowski MC, Blackwell TS, Yull FE. Connelly L, et al. Breast Cancer Res. 2011 Aug 31;13(4):R83. doi: 10.1186/bcr2935. Breast Cancer Res. 2011. PMID: 21884585 Free PMC article.

9

Tracking NF-κB activity in tumor cells during ovarian cancer progression in a syngeneic mouse model.

Wilson AJ, Barham W, Saskowski J, Tikhomirov O, Chen L, Lee HJ, Yull F, Khabele D. Wilson AJ, et al. J Ovarian Res. 2013 Sep 10;6(1):63. doi: 10.1186/1757-2215-6-63. J Ovarian Res. 2013. PMID: 24020521 Free PMC article.

10

Myeloid IKKβ promotes antitumor immunity by modulating CCL11 and the innate immune response.

Yang J, Hawkins OE, Barham W, Gilchuk P, Boothby M, Ayers GD, Joyce S, Karin M, Yull FE, Richmond A. Yang J, et al. Cancer Res. 2014 Dec 15;74(24):7274-84. doi: 10.1158/0008-5472.CAN-14-1091. Epub 2014 Oct 21. Cancer Res. 2014. PMID: 25336190 Free PMC article.

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