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Multidrug resistance protein 4 (MRP4) polymorphisms impact the 6-mercaptopurine dose tolerance during maintenance therapy in Japanese childhood acute lymphoblastic leukemia.
Tanaka Y, Manabe A, Fukushima H, Suzuki R, Nakadate H, Kondoh K, Nakamura K, Koh K, Fukushima T, Tsuchida M, Koike K, Kiyokawa N, Noguchi E, Sumazaki R, Komiyama T. Tanaka Y, et al. Pharmacogenomics J. 2015 Aug;15(4):380-4. doi: 10.1038/tpj.2014.74. Epub 2014 Nov 18. Pharmacogenomics J. 2015. PMID: 25403995
Lower doses of 6-mercaptopurine/azathioprine bring enough clinical efficacy and therapeutic concentration of erythrocyte 6-mercaptopurine metabolite in Japanese IBD patients.
Komiyama T, Yajima T, Kubota R, Iwao Y, Sakuraba A, Funakoshi S, Negishi K, Minami I, Tanaka Y, Mae H, Hibi T. Komiyama T, et al. Among authors: tanaka y. J Crohns Colitis. 2008 Dec;2(4):315-21. doi: 10.1016/j.crohns.2008.05.002. Epub 2008 Jul 3. J Crohns Colitis. 2008. PMID: 21172230 No abstract available.
[Pharmacogenomics for leukemia treatment].
Tanaka Y. Tanaka Y. Rinsho Ketsueki. 2016 Jul;57(7):910-8. doi: 10.11406/rinketsu.57.910. Rinsho Ketsueki. 2016. PMID: 27498738 Japanese.
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