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Fluconazole alters the polysaccharide capsule of Cryptococcus gattii and leads to distinct behaviors in murine Cryptococcosis.
Santos JR, Holanda RA, Frases S, Bravim M, Araujo Gde S, Santos PC, Costa MC, Ribeiro MJ, Ferreira GF, Baltazar LM, Miranda AS, Oliveira DB, Santos CM, Fontes AC, Gouveia LF, Resende-Stoianoff MA, Abrahão JS, Teixeira AL, Paixão TA, Souza DG, Santos DA. Santos JR, et al. Among authors: araujo gde s. PLoS One. 2014 Nov 13;9(11):e112669. doi: 10.1371/journal.pone.0112669. eCollection 2014. PLoS One. 2014. PMID: 25392951 Free PMC article.
Capsules from pathogenic and non-pathogenic Cryptococcus spp. manifest significant differences in structure and ability to protect against phagocytic cells.
Araujo Gde S, Fonseca FL, Pontes B, Torres A, Cordero RJ, Zancopé-Oliveira RM, Casadevall A, Viana NB, Nimrichter L, Rodrigues ML, Garcia ES, Souza Wd, Frases S. Araujo Gde S, et al. PLoS One. 2012;7(1):e29561. doi: 10.1371/journal.pone.0029561. Epub 2012 Jan 12. PLoS One. 2012. PMID: 22253734 Free PMC article.
Binding of the wheat germ lectin to Cryptococcus neoformans chitooligomers affects multiple mechanisms required for fungal pathogenesis.
Fonseca FL, Guimarães AJ, Kmetzsch L, Dutra FF, Silva FD, Taborda CP, Araujo Gde S, Frases S, Staats CC, Bozza MT, Schrank A, Vainstein MH, Nimrichter L, Casadevall A, Rodrigues ML. Fonseca FL, et al. Among authors: araujo gde s. Fungal Genet Biol. 2013 Nov;60:64-73. doi: 10.1016/j.fgb.2013.04.005. Epub 2013 Apr 19. Fungal Genet Biol. 2013. PMID: 23608320 Free PMC article.