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Efficient reverse genetics reveals genetic determinants of budding and fusogenic differences between Nipah and Hendra viruses and enables real-time monitoring of viral spread in small animal models of henipavirus infection.
Yun T, Park A, Hill TE, Pernet O, Beaty SM, Juelich TL, Smith JK, Zhang L, Wang YE, Vigant F, Gao J, Wu P, Lee B, Freiberg AN. Yun T, et al. Among authors: vigant f. J Virol. 2015 Jan 15;89(2):1242-53. doi: 10.1128/JVI.02583-14. Epub 2014 Nov 12. J Virol. 2015. PMID: 25392218 Free PMC article.
Nipah virus envelope-pseudotyped lentiviruses efficiently target ephrinB2-positive stem cell populations in vitro and bypass the liver sink when administered in vivo.
Palomares K, Vigant F, Van Handel B, Pernet O, Chikere K, Hong P, Sherman SP, Patterson M, An DS, Lowry WE, Mikkola HK, Morizono K, Pyle AD, Lee B. Palomares K, et al. Among authors: vigant f. J Virol. 2013 Feb;87(4):2094-108. doi: 10.1128/JVI.02032-12. Epub 2012 Nov 28. J Virol. 2013. PMID: 23192877 Free PMC article.
A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion.
Vigant F, Lee J, Hollmann A, Tanner LB, Akyol Ataman Z, Yun T, Shui G, Aguilar HC, Zhang D, Meriwether D, Roman-Sosa G, Robinson LR, Juelich TL, Buczkowski H, Chou S, Castanho MA, Wolf MC, Smith JK, Banyard A, Kielian M, Reddy S, Wenk MR, Selke M, Santos NC, Freiberg AN, Jung ME, Lee B. Vigant F, et al. PLoS Pathog. 2013;9(4):e1003297. doi: 10.1371/journal.ppat.1003297. Epub 2013 Apr 18. PLoS Pathog. 2013. PMID: 23637597 Free PMC article.
Efficient and Robust Paramyxoviridae Reverse Genetics Systems.
Beaty SM, Park A, Won ST, Hong P, Lyons M, Vigant F, Freiberg AN, tenOever BR, Duprex WP, Lee B. Beaty SM, et al. Among authors: vigant f. mSphere. 2017 Mar 29;2(2):e00376-16. doi: 10.1128/mSphere.00376-16. eCollection 2017 Mar-Apr. mSphere. 2017. PMID: 28405630 Free PMC article.
Broad-spectrum antivirals against viral fusion.
Vigant F, Santos NC, Lee B. Vigant F, et al. Nat Rev Microbiol. 2015 Jul;13(7):426-37. doi: 10.1038/nrmicro3475. Epub 2015 Jun 15. Nat Rev Microbiol. 2015. PMID: 26075364 Free PMC article. Review.
Positive reinforcement for viruses.
Vigant F, Jung M, Lee B. Vigant F, et al. Chem Biol. 2010 Oct 29;17(10):1049-51. doi: 10.1016/j.chembiol.2010.10.002. Chem Biol. 2010. PMID: 21035726 Free PMC article.
22 results