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Page 1
Skin Fibrosis and Recovery Is Dependent on Wnt Activation via DPP4.
Jussila AR, Zhang B, Caves E, Kirti S, Steele M, Hamburg-Shields E, Lydon J, Ying Y, Lafyatis R, Rajagopalan S, Horsley V, Atit RP. Jussila AR, et al. Among authors: lafyatis r. J Invest Dermatol. 2022 Jun;142(6):1597-1606.e9. doi: 10.1016/j.jid.2021.10.025. Epub 2021 Nov 20. J Invest Dermatol. 2022. PMID: 34808238 Free PMC article.
Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma.
Bhattacharyya S, Kelley K, Melichian DS, Tamaki Z, Fang F, Su Y, Feng G, Pope RM, Budinger GR, Mutlu GM, Lafyatis R, Radstake T, Feghali-Bostwick C, Varga J. Bhattacharyya S, et al. Among authors: lafyatis r. Am J Pathol. 2013 Jan;182(1):192-205. doi: 10.1016/j.ajpath.2012.09.007. Epub 2012 Nov 7. Am J Pathol. 2013. PMID: 23141927 Free PMC article.
Altered Dermal Fibroblasts in Systemic Sclerosis Display Podoplanin and CD90.
Nazari B, Rice LM, Stifano G, Barron AM, Wang YM, Korndorf T, Lee J, Bhawan J, Lafyatis R, Browning JL. Nazari B, et al. Among authors: lafyatis r. Am J Pathol. 2016 Oct;186(10):2650-64. doi: 10.1016/j.ajpath.2016.06.020. Epub 2016 Aug 23. Am J Pathol. 2016. PMID: 27565038 Free PMC article.
Limited cutaneous systemic sclerosis skin demonstrates distinct molecular subsets separated by a cardiovascular development gene expression signature.
Derrett-Smith EC, Martyanov V, Chighizola CB, Moinzadeh P, Campochiaro C, Khan K, Wood TA, Meroni PL, Abraham DJ, Ong VH, Lafyatis R, Whitfield ML, Denton CP. Derrett-Smith EC, et al. Among authors: lafyatis r. Arthritis Res Ther. 2017 Jul 4;19(1):156. doi: 10.1186/s13075-017-1360-7. Arthritis Res Ther. 2017. PMID: 28676069 Free PMC article.
Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis.
Ma F, Tsou PS, Gharaee-Kermani M, Plazyo O, Xing X, Kirma J, Wasikowski R, Hile GA, Harms PW, Jiang Y, Xing E, Nakamura M, Ochocki D, Brodie WD, Pillai S, Maverakis E, Pellegrini M, Modlin RL, Varga J, Tsoi LC, Lafyatis R, Kahlenberg JM, Billi AC, Khanna D, Gudjonsson JE. Ma F, et al. Among authors: lafyatis r. Nat Commun. 2024 Jan 3;15(1):210. doi: 10.1038/s41467-023-44645-6. Nat Commun. 2024. PMID: 38172207 Free PMC article.
258 results