Alderson TR - Search Results

1

The specialized Hsp70 (HscA) interdomain linker binds to its nucleotide-binding domain and stimulates ATP hydrolysis in both cis and trans configurations.

Alderson TR, Kim JH, Cai K, Frederick RO, Tonelli M, Markley JL. Alderson TR, et al. Biochemistry. 2014 Nov 25;53(46):7148-59. doi: 10.1021/bi5010552. Epub 2014 Nov 11. Biochemistry. 2014. PMID: 25372495 Free PMC article.

2

Dynamical Structures of Hsp70 and Hsp70-Hsp40 Complexes.

Alderson TR, Kim JH, Markley JL. Alderson TR, et al. Structure. 2016 Jul 6;24(7):1014-30. doi: 10.1016/j.str.2016.05.011. Epub 2016 Jun 23. Structure. 2016. PMID: 27345933 Free PMC article. Review.

3

Nucleotide-dependent interactions within a specialized Hsp70/Hsp40 complex involved in Fe-S cluster biogenesis.

Kim JH, Alderson TR, Frederick RO, Markley JL. Kim JH, et al. Among authors: alderson tr. J Am Chem Soc. 2014 Aug 20;136(33):11586-9. doi: 10.1021/ja5055252. Epub 2014 Aug 6. J Am Chem Soc. 2014. PMID: 25080945 Free PMC article.

4

Biophysical characterization of α-synuclein and its controversial structure.

Alderson TR, Markley JL. Alderson TR, et al. Intrinsically Disord Proteins. 2013 Jan 1;1(1):18-39. doi: 10.4161/idp.26255. Epub 2013 Apr 1. Intrinsically Disord Proteins. 2013. PMID: 24634806 Free PMC article. Review.

5

Tangled web of interactions among proteins involved in iron-sulfur cluster assembly as unraveled by NMR, SAXS, chemical crosslinking, and functional studies.

Kim JH, Bothe JR, Alderson TR, Markley JL. Kim JH, et al. Among authors: alderson tr. Biochim Biophys Acta. 2015 Jun;1853(6):1416-28. doi: 10.1016/j.bbamcr.2014.11.020. Epub 2014 Nov 22. Biochim Biophys Acta. 2015. PMID: 25450980 Free PMC article. Review.

6

Monitoring ¹⁵N Chemical Shifts During Protein Folding by Pressure-Jump NMR.

Charlier C, Courtney JM, Alderson TR, Anfinrud P, Bax A. Charlier C, et al. Among authors: alderson tr. J Am Chem Soc. 2018 Jul 5;140(26):8096-8099. doi: 10.1021/jacs.8b04833. Epub 2018 Jun 25. J Am Chem Soc. 2018. PMID: 29923716 Free PMC article.

7

Monitoring Hydrogen Exchange During Protein Folding by Fast Pressure Jump NMR Spectroscopy.

Alderson TR, Charlier C, Torchia DA, Anfinrud P, Bax A. Alderson TR, et al. J Am Chem Soc. 2017 Aug 16;139(32):11036-11039. doi: 10.1021/jacs.7b06676. Epub 2017 Aug 7. J Am Chem Soc. 2017. PMID: 28766333 Free PMC article.

8

Conditional Disorder in Small Heat-shock Proteins.

Alderson TR, Ying J, Bax A, Benesch JLP, Baldwin AJ. Alderson TR, et al. J Mol Biol. 2020 Apr 17;432(9):3033-3049. doi: 10.1016/j.jmb.2020.02.003. Epub 2020 Feb 17. J Mol Biol. 2020. PMID: 32081587 Free PMC article.

9

Proline isomerization in the C-terminal region of HSP27.

Alderson TR, Benesch JLP, Baldwin AJ. Alderson TR, et al. Cell Stress Chaperones. 2017 Jul;22(4):639-651. doi: 10.1007/s12192-017-0791-z. Epub 2017 May 25. Cell Stress Chaperones. 2017. PMID: 28547731 Free PMC article.

10

Local unfolding of the HSP27 monomer regulates chaperone activity.

Alderson TR, Roche J, Gastall HY, Dias DM, Pritišanac I, Ying J, Bax A, Benesch JLP, Baldwin AJ. Alderson TR, et al. Nat Commun. 2019 Mar 6;10(1):1068. doi: 10.1038/s41467-019-08557-8. Nat Commun. 2019. PMID: 30842409 Free PMC article.

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