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54 results

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Page 1
Efficacy and safety of combined prolonged-release oxycodone and naloxone in the management of moderate/severe chronic non-malignant pain: results of a prospectively designed pooled analysis of two randomised, double-blind clinical trials.
Löwenstein O, Leyendecker P, Lux EA, Blagden M, Simpson KH, Hopp M, Bosse B, Reimer K. Löwenstein O, et al. Among authors: bosse b. BMC Clin Pharmacol. 2010 Sep 29;10:12. doi: 10.1186/1472-6904-10-12. BMC Clin Pharmacol. 2010. PMID: 20920236 Free PMC article. Clinical Trial.
A randomized, double-blind, active-controlled, double-dummy, parallel-group study to determine the safety and efficacy of oxycodone/naloxone prolonged-release tablets in patients with moderate/severe, chronic cancer pain.
Ahmedzai SH, Nauck F, Bar-Sela G, Bosse B, Leyendecker P, Hopp M. Ahmedzai SH, et al. Among authors: bosse b. Palliat Med. 2012 Jan;26(1):50-60. doi: 10.1177/0269216311418869. Epub 2011 Sep 21. Palliat Med. 2012. PMID: 21937568 Free PMC article. Clinical Trial.
Sleep and Quality of Life Under Prolonged Release Oxycodone/Naloxone for Severe Restless Legs Syndrome: An Analysis of Secondary Efficacy Variables of a Double-Blind, Randomized, Placebo-Controlled Study with an Open-Label Extension.
Oertel WH, Hallström Y, Saletu-Zyhlarz GM, Hopp M, Bosse B, Trenkwalder C; RELOXYN Study Group. Oertel WH, et al. Among authors: bosse b. CNS Drugs. 2016 Aug;30(8):749-60. doi: 10.1007/s40263-016-0372-1. CNS Drugs. 2016. PMID: 27401882 Free PMC article. Clinical Trial.
Long-term efficacy and safety of oxycodone-naloxone prolonged-release formulation (up to 180/90 mg daily) - results of the open-label extension phase of a phase III multicenter, multiple-dose, randomized, controlled study.
Dupoiron D, Stachowiak A, Loewenstein O, Ellery A, Kremers W, Bosse B, Hopp M. Dupoiron D, et al. Among authors: bosse b. Eur J Pain. 2017 Oct;21(9):1485-1494. doi: 10.1002/ejp.1050. Epub 2017 May 4. Eur J Pain. 2017. PMID: 28474460 Free PMC article. Clinical Trial.
Fixed-ratio combination oxycodone/naloxone compared with oxycodone alone for the relief of opioid-induced constipation in moderate-to-severe noncancer pain.
Simpson K, Leyendecker P, Hopp M, Müller-Lissner S, Löwenstein O, De Andrés J, Troy Ferrarons J, Bosse B, Krain B, Nichols T, Kremers W, Reimer K. Simpson K, et al. Among authors: bosse b. Curr Med Res Opin. 2008 Dec;24(12):3503-12. doi: 10.1185/03007990802584454. Curr Med Res Opin. 2008. PMID: 19032132 Clinical Trial.
Prolonged release oxycodone-naloxone for treatment of severe restless legs syndrome after failure of previous treatment: a double-blind, randomised, placebo-controlled trial with an open-label extension.
Trenkwalder C, Beneš H, Grote L, García-Borreguero D, Högl B, Hopp M, Bosse B, Oksche A, Reimer K, Winkelmann J, Allen RP, Kohnen R; RELOXYN Study Group. Trenkwalder C, et al. Among authors: bosse b. Lancet Neurol. 2013 Dec;12(12):1141-50. doi: 10.1016/S1474-4422(13)70239-4. Epub 2013 Oct 18. Lancet Neurol. 2013. PMID: 24140442 Clinical Trial.
The Socioeconomic Costs of the Undertreatment of Pain.
Hopp M, Bosse B, Dunlop W. Hopp M, et al. Among authors: bosse b. Value Health. 2014 Nov;17(7):A785. doi: 10.1016/j.jval.2014.08.400. Epub 2014 Oct 26. Value Health. 2014. PMID: 27202923 Free article. No abstract available.
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