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JPC-2997, a new aminomethylphenol with high in vitro and in vivo antimalarial activities against blood stages of Plasmodium.
Birrell GW, Chavchich M, Ager AL, Shieh HM, Heffernan GD, Zhao W, Krasucki PE, Saionz KW, Terpinski J, Schiehser GA, Jacobus LR, Shanks GD, Jacobus DP, Edstein MD. Birrell GW, et al. Among authors: terpinski j. Antimicrob Agents Chemother. 2015 Jan;59(1):170-7. doi: 10.1128/AAC.03762-14. Epub 2014 Oct 20. Antimicrob Agents Chemother. 2015. PMID: 25331702 Free PMC article.
Novel diaryl ureas with efficacy in a mouse model of malaria.
Anderson JW, Sarantakis D, Terpinski J, Kumar TR, Tsai HC, Kuo M, Ager AL, Jacobs WR Jr, Schiehser GA, Ekins S, Sacchettini JC, Jacobus DP, Fidock DA, Freundlich JS. Anderson JW, et al. Among authors: terpinski j. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1022-5. doi: 10.1016/j.bmcl.2012.12.022. Epub 2012 Dec 20. Bioorg Med Chem Lett. 2013. PMID: 23313245 Free PMC article.
In vitro efficacy of next-generation dihydrotriazines and biguanides against babesiosis and malaria parasites.
Vydyam P, Chand M, Gihaz S, Renard I, Heffernan GD, Jacobus LR, Jacobus DP, Saionz KW, Shah R, Shieh H-M, Terpinski J, Zhao W, Cornillot E, Ben Mamoun C. Vydyam P, et al. Among authors: terpinski j. Antimicrob Agents Chemother. 2024 Sep 4;68(9):e0042324. doi: 10.1128/aac.00423-24. Epub 2024 Aug 13. Antimicrob Agents Chemother. 2024. PMID: 39136469 Free PMC article.