Jones JP - Search Results

1

Inhibition of human aldehyde oxidase activity by diet-derived constituents: structural influence, enzyme-ligand interactions, and clinical relevance.

Barr JT, Jones JP, Oberlies NH, Paine MF. Barr JT, et al. Among authors: jones jp. Drug Metab Dispos. 2015 Jan;43(1):34-41. doi: 10.1124/dmd.114.061192. Epub 2014 Oct 17. Drug Metab Dispos. 2015. PMID: 25326286 Free PMC article.

2

Inhibition of human liver aldehyde oxidase: implications for potential drug-drug interactions.

Barr JT, Jones JP. Barr JT, et al. Among authors: jones jp. Drug Metab Dispos. 2011 Dec;39(12):2381-6. doi: 10.1124/dmd.111.041806. Epub 2011 Sep 22. Drug Metab Dispos. 2011. PMID: 21940905 Free PMC article.

3

Evidence for substrate-dependent inhibition profiles for human liver aldehyde oxidase.

Barr JT, Jones JP. Barr JT, et al. Among authors: jones jp. Drug Metab Dispos. 2013 Jan;41(1):24-9. doi: 10.1124/dmd.112.048546. Epub 2012 Sep 20. Drug Metab Dispos. 2013. PMID: 22996261 Free PMC article.

4

Evaluation of rhesus monkey and guinea pig hepatic cytosol fractions as models for human aldehyde oxidase.

Choughule KV, Barr JT, Jones JP. Choughule KV, et al. Among authors: jones jp. Drug Metab Dispos. 2013 Oct;41(10):1852-8. doi: 10.1124/dmd.113.052985. Epub 2013 Aug 5. Drug Metab Dispos. 2013. PMID: 23918666 Free PMC article.

5

Absolute quantification of aldehyde oxidase protein in human liver using liquid chromatography-tandem mass spectrometry.

Barr JT, Jones JP, Joswig-Jones CA, Rock DA. Barr JT, et al. Among authors: jones jp. Mol Pharm. 2013 Oct 7;10(10):3842-9. doi: 10.1021/mp4003046. Epub 2013 Sep 19. Mol Pharm. 2013. PMID: 24006961 Free PMC article.

6

Why do most human liver cytosol preparations lack xanthine oxidase activity?

Barr JT, Choughule KV, Nepal S, Wong T, Chaudhry AS, Joswig-Jones CA, Zientek M, Strom SC, Schuetz EG, Thummel KE, Jones JP. Barr JT, et al. Among authors: jones jp. Drug Metab Dispos. 2014 Apr;42(4):695-9. doi: 10.1124/dmd.113.056374. Epub 2014 Jan 15. Drug Metab Dispos. 2014. PMID: 24430612 Free PMC article.

7

Enzyme kinetics, inhibition, and regioselectivity of aldehyde oxidase.

Barr JT, Choughule K, Jones JP. Barr JT, et al. Among authors: jones jp. Methods Mol Biol. 2014;1113:167-86. doi: 10.1007/978-1-62703-758-7_9. Methods Mol Biol. 2014. PMID: 24523113 Review.

8

A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834.

Sodhi JK, Wong S, Kirkpatrick DS, Liu L, Khojasteh SC, Hop CE, Barr JT, Jones JP, Halladay JS. Sodhi JK, et al. Among authors: jones jp. Drug Metab Dispos. 2015 Jun;43(6):908-15. doi: 10.1124/dmd.114.061804. Epub 2015 Apr 6. Drug Metab Dispos. 2015. PMID: 25845827 Free PMC article.

9

Enzyme Kinetics, Pharmacokinetics, and Inhibition of Aldehyde Oxidase.

Paragas EM, Choughule K, Jones JP, Barr JT. Paragas EM, et al. Among authors: jones jp. Methods Mol Biol. 2021;2342:257-284. doi: 10.1007/978-1-0716-1554-6_10. Methods Mol Biol. 2021. PMID: 34272698

10

Site-Directed Mutagenesis at the Molybdenum Pterin Cofactor Site of the Human Aldehyde Oxidase: Interrogating the Kinetic Differences Between Human and Cynomolgus Monkey.

Abbasi A, Joswig-Jones CA, Jones JP. Abbasi A, et al. Among authors: jones jp. Drug Metab Dispos. 2020 Dec;48(12):1364-1371. doi: 10.1124/dmd.120.000187. Epub 2020 Oct 5. Drug Metab Dispos. 2020. PMID: 33020066 Free PMC article.

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