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A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior.
Vardy E, Robinson JE, Li C, Olsen RHJ, DiBerto JF, Giguere PM, Sassano FM, Huang XP, Zhu H, Urban DJ, White KL, Rittiner JE, Crowley NA, Pleil KE, Mazzone CM, Mosier PD, Song J, Kash TL, Malanga CJ, Krashes MJ, Roth BL. Vardy E, et al. Among authors: zhu h. Neuron. 2015 May 20;86(4):936-946. doi: 10.1016/j.neuron.2015.03.065. Epub 2015 Apr 30. Neuron. 2015. PMID: 25937170 Free PMC article.
Silencing synapses with DREADDs.
Zhu H, Roth BL. Zhu H, et al. Neuron. 2014 May 21;82(4):723-5. doi: 10.1016/j.neuron.2014.05.002. Neuron. 2014. PMID: 24853931 Free PMC article.
DREADD: a chemogenetic GPCR signaling platform.
Zhu H, Roth BL. Zhu H, et al. Int J Neuropsychopharmacol. 2014 Oct 31;18(1):pyu007. doi: 10.1093/ijnp/pyu007. Int J Neuropsychopharmacol. 2014. PMID: 25522378 Free PMC article.
Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65.
Huang XP, Karpiak J, Kroeze WK, Zhu H, Chen X, Moy SS, Saddoris KA, Nikolova VD, Farrell MS, Wang S, Mangano TJ, Deshpande DA, Jiang A, Penn RB, Jin J, Koller BH, Kenakin T, Shoichet BK, Roth BL. Huang XP, et al. Among authors: zhu h. Nature. 2015 Nov 26;527(7579):477-83. doi: 10.1038/nature15699. Epub 2015 Nov 9. Nature. 2015. PMID: 26550826 Free PMC article.
Elucidation of The Behavioral Program and Neuronal Network Encoded by Dorsal Raphe Serotonergic Neurons.
Urban DJ, Zhu H, Marcinkiewcz CA, Michaelides M, Oshibuchi H, Rhea D, Aryal DK, Farrell MS, Lowery-Gionta E, Olsen RH, Wetsel WC, Kash TL, Hurd YL, Tecott LH, Roth BL. Urban DJ, et al. Among authors: zhu h. Neuropsychopharmacology. 2016 Apr;41(5):1404-15. doi: 10.1038/npp.2015.293. Epub 2015 Sep 18. Neuropsychopharmacology. 2016. PMID: 26383016 Free PMC article.
Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models.
Cheng J, Giguere PM, Schmerberg CM, Pogorelov VM, Rodriguiz RM, Huang XP, Zhu H, McCorvy JD, Wetsel WC, Roth BL, Kozikowski AP. Cheng J, et al. Among authors: zhu h. J Med Chem. 2016 Jan 28;59(2):578-91. doi: 10.1021/acs.jmedchem.5b01153. Epub 2016 Jan 13. J Med Chem. 2016. PMID: 26704965 Free PMC article.
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