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An absence of nuclear lamins in keratinocytes leads to ichthyosis, defective epidermal barrier function, and intrusion of nuclear membranes and endoplasmic reticulum into the nuclear chromatin.
Jung HJ, Tatar A, Tu Y, Nobumori C, Yang SH, Goulbourne CN, Herrmann H, Fong LG, Young SG. Jung HJ, et al. Among authors: goulbourne cn. Mol Cell Biol. 2014 Dec;34(24):4534-44. doi: 10.1128/MCB.00997-14. Epub 2014 Oct 13. Mol Cell Biol. 2014. PMID: 25312645 Free PMC article.
Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice.
Weinstein MM, Goulbourne CN, Davies BS, Tu Y, Barnes RH 2nd, Watkins SM, Davis R, Reue K, Tontonoz P, Beigneux AP, Fong LG, Young SG. Weinstein MM, et al. Among authors: goulbourne cn. Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):230-5. doi: 10.1161/ATVBAHA.111.241406. Epub 2011 Dec 15. Arterioscler Thromb Vasc Biol. 2012. PMID: 22173228 Free PMC article.
IDOL stimulates clathrin-independent endocytosis and multivesicular body-mediated lysosomal degradation of the low-density lipoprotein receptor.
Scotti E, Calamai M, Goulbourne CN, Zhang L, Hong C, Lin RR, Choi J, Pilch PF, Fong LG, Zou P, Ting AY, Pavone FS, Young SG, Tontonoz P. Scotti E, et al. Among authors: goulbourne cn. Mol Cell Biol. 2013 Apr;33(8):1503-14. doi: 10.1128/MCB.01716-12. Epub 2013 Feb 4. Mol Cell Biol. 2013. PMID: 23382078 Free PMC article.
42 results