Soares J - Search Results

1

Oxazoloisoindolinones with in vitro antitumor activity selectively activate a p53-pathway through potential inhibition of the p53-MDM2 interaction.

Soares J, Pereira NA, Monteiro Â, Leão M, Bessa C, Dos Santos DJ, Raimundo L, Queiroz G, Bisio A, Inga A, Pereira C, Santos MM, Saraiva L. Soares J, et al. Eur J Pharm Sci. 2015 Jan 23;66:138-47. doi: 10.1016/j.ejps.2014.10.006. Epub 2014 Oct 13. Eur J Pharm Sci. 2015. PMID: 25312347

2

Aspartic vinyl sulfones: inhibitors of a caspase-3-dependent pathway.

Glória PM, Coutinho I, Gonçalves LM, Baptista C, Soares J, Newton AS, Moreira R, Saraiva L, Santos MM. Glória PM, et al. Among authors: soares j. Eur J Med Chem. 2011 Jun;46(6):2141-6. doi: 10.1016/j.ejmech.2011.02.067. Epub 2011 Mar 5. Eur J Med Chem. 2011. PMID: 21439692

3

Rapid-behaviour responses as a reliable indicator of estrogenic chemical toxicity in zebrafish juveniles.

Sárria MP, Soares J, Vieira MN, Castro LF, Santos MM, Monteiro NM. Sárria MP, et al. Among authors: soares j. Chemosphere. 2011 Nov;85(10):1543-7. doi: 10.1016/j.chemosphere.2011.07.048. Epub 2011 Sep 8. Chemosphere. 2011. PMID: 21862102

4

New insights into cancer-related proteins provided by the yeast model.

Pereira C, Coutinho I, Soares J, Bessa C, Leão M, Saraiva L. Pereira C, et al. Among authors: soares j. FEBS J. 2012 Mar;279(5):697-712. doi: 10.1111/j.1742-4658.2012.08477.x. Epub 2012 Feb 10. FEBS J. 2012. PMID: 22239976 Free article. Review.

5

Zebrafish (Danio rerio) life-cycle exposure to chronic low doses of ethinylestradiol modulates p53 gene transcription within the gonads, but not NER pathways.

Soares J, Castro LF, Reis-Henriques MA, Monteiro NM, Santos MM. Soares J, et al. Ecotoxicology. 2012 Jul;21(5):1513-22. doi: 10.1007/s10646-012-0905-4. Epub 2012 Apr 28. Ecotoxicology. 2012. PMID: 22543959

6

New therapeutic strategies for cancer and neurodegeneration emerging from yeast cell-based systems.

Pereira C, Leão M, Soares J, Bessa C, Saraiva L. Pereira C, et al. Among authors: soares j. Curr Pharm Des. 2012;18(27):4223-35. doi: 10.2174/138161212802430422. Curr Pharm Des. 2012. PMID: 22650181 Review.

7

Contribution of yeast models to neurodegeneration research.

Pereira C, Bessa C, Soares J, Leão M, Saraiva L. Pereira C, et al. Among authors: soares j. J Biomed Biotechnol. 2012;2012:941232. doi: 10.1155/2012/941232. Epub 2012 Jul 15. J Biomed Biotechnol. 2012. PMID: 22910375 Free PMC article. Review.

8

Novel simplified yeast-based assays of regulators of p53-MDMX interaction and p53 transcriptional activity.

Leão M, Gomes S, Soares J, Bessa C, Maciel C, Ciribilli Y, Pereira C, Inga A, Saraiva L. Leão M, et al. Among authors: soares j. FEBS J. 2013 Dec;280(24):6498-507. doi: 10.1111/febs.12552. Epub 2013 Oct 23. FEBS J. 2013. PMID: 24119020 Free article.

9

Studying p53 family proteins in yeast: induction of autophagic cell death and modulation by interactors and small molecules.

Leão M, Gomes S, Bessa C, Soares J, Raimundo L, Monti P, Fronza G, Pereira C, Saraiva L. Leão M, et al. Among authors: soares j. Exp Cell Res. 2015 Jan 1;330(1):164-77. doi: 10.1016/j.yexcr.2014.09.028. Epub 2014 Sep 28. Exp Cell Res. 2015. PMID: 25265062

10

A tryptophanol-derived oxazolopiperidone lactam is cytotoxic against tumors via inhibition of p53 interaction with murine double minute proteins.

Soares J, Raimundo L, Pereira NA, dos Santos DJ, Pérez M, Queiroz G, Leão M, Santos MM, Saraiva L. Soares J, et al. Pharmacol Res. 2015 May-Jun;95-96:42-52. doi: 10.1016/j.phrs.2015.03.006. Epub 2015 Mar 23. Pharmacol Res. 2015. PMID: 25814188 Free article.

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