Fowler CJ - Search Results

1

A reversible and selective inhibitor of monoacylglycerol lipase ameliorates multiple sclerosis.

Hernández-Torres G, Cipriano M, Hedén E, Björklund E, Canales Á, Zian D, Feliú A, Mecha M, Guaza C, Fowler CJ, Ortega-Gutiérrez S, López-Rodríguez ML. Hernández-Torres G, et al. Among authors: fowler cj. Angew Chem Int Ed Engl. 2014 Dec 8;53(50):13765-70. doi: 10.1002/anie.201407807. Epub 2014 Oct 8. Angew Chem Int Ed Engl. 2014. PMID: 25298214

2

Structure-activity relationship of a new series of reversible dual monoacylglycerol lipase/fatty acid amide hydrolase inhibitors.

Cisneros JA, Björklund E, González-Gil I, Hu Y, Canales A, Medrano FJ, Romero A, Ortega-Gutiérrez S, Fowler CJ, López-Rodríguez ML. Cisneros JA, et al. Among authors: fowler cj. J Med Chem. 2012 Jan 26;55(2):824-36. doi: 10.1021/jm201327p. Epub 2012 Jan 17. J Med Chem. 2012. PMID: 22185522

3

Structure-activity relationship of a series of inhibitors of monoacylglycerol hydrolysis--comparison with effects upon fatty acid amide hydrolase.

Cisneros JA, Vandevoorde S, Ortega-Gutiérrez S, Paris C, Fowler CJ, López-Rodríguez ML. Cisneros JA, et al. Among authors: fowler cj. J Med Chem. 2007 Oct 4;50(20):5012-23. doi: 10.1021/jm070642y. Epub 2007 Sep 1. J Med Chem. 2007. PMID: 17764163

4

Design, synthesis and biological evaluation of new endocannabinoid transporter inhibitors.

López-Rodríguez ML, Viso A, Ortega-Gutiérrez S, Fowler CJ, Tiger G, de Lago E, Fernández-Ruiz J, Ramos JA. López-Rodríguez ML, et al. Among authors: fowler cj. Eur J Med Chem. 2003 Apr;38(4):403-12. doi: 10.1016/s0223-5234(03)00045-x. Eur J Med Chem. 2003. PMID: 12750028

5

The influence of monoacylglycerol lipase inhibition upon the expression of epidermal growth factor receptor in human PC-3 prostate cancer cells.

Cipriano M, Gouveia-Figueira S, Persson E, Nording M, Fowler CJ. Cipriano M, et al. Among authors: fowler cj. BMC Res Notes. 2014 Jul 10;7:441. doi: 10.1186/1756-0500-7-441. BMC Res Notes. 2014. PMID: 25012825 Free PMC article.

6

Inhibition of monoacylglycerol lipase by troglitazone, N-arachidonoyl dopamine and the irreversible inhibitor JZL184: comparison of two different assays.

Björklund E, Norén E, Nilsson J, Fowler CJ. Björklund E, et al. Among authors: fowler cj. Br J Pharmacol. 2010 Dec;161(7):1512-26. doi: 10.1111/j.1476-5381.2010.00974.x. Br J Pharmacol. 2010. PMID: 20735405 Free PMC article.

7

Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: comparison with effects on fatty acid amidohydrolase.

López-Rodríguez ML, Viso A, Ortega-Gutiérrez S, Fowler CJ, Tiger G, de Lago E, Fernández-Ruiz J, Ramos JA. López-Rodríguez ML, et al. Among authors: fowler cj. J Med Chem. 2003 Apr 10;46(8):1512-22. doi: 10.1021/jm0210818. J Med Chem. 2003. PMID: 12672252

8

Inhibition of fatty acid amide hydrolase and cyclooxygenase by the N-(3-methylpyridin-2-yl)amide derivatives of flurbiprofen and naproxen.

Cipriano M, Björklund E, Wilson AA, Congiu C, Onnis V, Fowler CJ. Cipriano M, et al. Among authors: fowler cj. Eur J Pharmacol. 2013 Nov 15;720(1-3):383-90. doi: 10.1016/j.ejphar.2013.09.065. Epub 2013 Oct 8. Eur J Pharmacol. 2013. PMID: 24120370

9

Inhibition of fatty acid amidohydrolase, the enzyme responsible for the metabolism of the endocannabinoid anandamide, by analogues of arachidonoyl-serotonin.

Fowler CJ, Tiger G, López-Rodríguez ML, Viso A, Ortega-Gutiérrez S, Ramos JA. Fowler CJ, et al. J Enzyme Inhib Med Chem. 2003 Jun;18(3):225-31. doi: 10.1080/1475636031000080216. J Enzyme Inhib Med Chem. 2003. PMID: 14506913 Free article.

10

Synthesis and evaluation of paracetamol esters as novel fatty acid amide hydrolase inhibitors.

Onnis V, Congiu C, Björklund E, Hempel F, Söderström E, Fowler CJ. Onnis V, et al. Among authors: fowler cj. J Med Chem. 2010 Mar 11;53(5):2286-98. doi: 10.1021/jm901891p. J Med Chem. 2010. PMID: 20143779

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