Orkin SH - Search Results

1

Myeloproliferative neoplasms can be initiated from a single hematopoietic stem cell expressing JAK2-V617F.

Lundberg P, Takizawa H, Kubovcakova L, Guo G, Hao-Shen H, Dirnhofer S, Orkin SH, Manz MG, Skoda RC. Lundberg P, et al. Among authors: orkin sh. J Exp Med. 2014 Oct 20;211(11):2213-30. doi: 10.1084/jem.20131371. Epub 2014 Oct 6. J Exp Med. 2014. PMID: 25288396 Free PMC article.

2

Expression of c-MYC under the control of GATA-1 regulatory sequences causes erythroleukemia in transgenic mice.

Skoda RC, Tsai SF, Orkin SH, Leder P. Skoda RC, et al. Among authors: orkin sh. J Exp Med. 1995 May 1;181(5):1603-13. doi: 10.1084/jem.181.5.1603. J Exp Med. 1995. PMID: 7722440 Free PMC article.

3

Hematopoietic development of vav-/- mouse embryonic stem cells.

Zhang R, Tsai FY, Orkin SH. Zhang R, et al. Among authors: orkin sh. Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12755-9. doi: 10.1073/pnas.91.26.12755. Proc Natl Acad Sci U S A. 1994. PMID: 7809116 Free PMC article.

4

Stem cell alchemy.

Orkin SH. Orkin SH. Nat Med. 2000 Nov;6(11):1212-3. doi: 10.1038/81303. Nat Med. 2000. PMID: 11062526 No abstract available.

5

Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo.

Yu C, Cantor AB, Yang H, Browne C, Wells RA, Fujiwara Y, Orkin SH. Yu C, et al. Among authors: orkin sh. J Exp Med. 2002 Jun 3;195(11):1387-95. doi: 10.1084/jem.20020656. J Exp Med. 2002. PMID: 12045237 Free PMC article.

6

Priming the hematopoietic pump.

Orkin SH. Orkin SH. Immunity. 2003 Nov;19(5):633-4. doi: 10.1016/s1074-7613(03)00302-9. Immunity. 2003. PMID: 14614848 Free article.

7

Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival.

Hock H, Meade E, Medeiros S, Schindler JW, Valk PJ, Fujiwara Y, Orkin SH. Hock H, et al. Among authors: orkin sh. Genes Dev. 2004 Oct 1;18(19):2336-41. doi: 10.1101/gad.1239604. Epub 2004 Sep 15. Genes Dev. 2004. PMID: 15371326 Free PMC article.

8

Tie2Cre-mediated gene ablation defines the stem-cell leukemia gene (SCL/tal1)-dependent window during hematopoietic stem-cell development.

Schlaeger TM, Mikkola HK, Gekas C, Helgadottir HB, Orkin SH. Schlaeger TM, et al. Among authors: orkin sh. Blood. 2005 May 15;105(10):3871-4. doi: 10.1182/blood-2004-11-4467. Epub 2005 Jan 27. Blood. 2005. PMID: 15677556 Free article.

9

The placenta is a niche for hematopoietic stem cells.

Gekas C, Dieterlen-Lièvre F, Orkin SH, Mikkola HK. Gekas C, et al. Among authors: orkin sh. Dev Cell. 2005 Mar;8(3):365-75. doi: 10.1016/j.devcel.2004.12.016. Dev Cell. 2005. PMID: 15737932 Free article.

10

Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis.

Rodrigues NP, Janzen V, Forkert R, Dombkowski DM, Boyd AS, Orkin SH, Enver T, Vyas P, Scadden DT. Rodrigues NP, et al. Among authors: orkin sh. Blood. 2005 Jul 15;106(2):477-84. doi: 10.1182/blood-2004-08-2989. Epub 2005 Apr 5. Blood. 2005. PMID: 15811962 Free article.

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