Holtzman DM - Search Results

1

Human neurons derived from induced pluripotent stem cells as a new platform for preclinical drug screening and development.

Liao F, Holtzman DM. Liao F, et al. Among authors: holtzman dm. JAMA Neurol. 2014 Dec;71(12):1475-6. doi: 10.1001/jamaneurol.2014.2802. JAMA Neurol. 2014. PMID: 25285675 No abstract available.

2

Fluctuations of CSF amyloid-beta levels: implications for a diagnostic and therapeutic biomarker.

Bateman RJ, Wen G, Morris JC, Holtzman DM. Bateman RJ, et al. Among authors: holtzman dm. Neurology. 2007 Feb 27;68(9):666-9. doi: 10.1212/01.wnl.0000256043.50901.e3. Neurology. 2007. PMID: 17325273

3

Extreme cerebrospinal fluid amyloid beta levels identify family with late-onset Alzheimer's disease presenilin 1 mutation.

Kauwe JS, Jacquart S, Chakraverty S, Wang J, Mayo K, Fagan AM, Holtzman DM, Morris JC, Goate AM. Kauwe JS, et al. Among authors: holtzman dm. Ann Neurol. 2007 May;61(5):446-53. doi: 10.1002/ana.21099. Ann Neurol. 2007. PMID: 17366635

4

A gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system.

Bateman RJ, Siemers ER, Mawuenyega KG, Wen G, Browning KR, Sigurdson WC, Yarasheski KE, Friedrich SW, Demattos RB, May PC, Paul SM, Holtzman DM. Bateman RJ, et al. Among authors: holtzman dm. Ann Neurol. 2009 Jul;66(1):48-54. doi: 10.1002/ana.21623. Ann Neurol. 2009. PMID: 19360898 Free PMC article. Clinical Trial.

5

CSF biomarkers of Alzheimer disease in HIV-associated neurologic disease.

Clifford DB, Fagan AM, Holtzman DM, Morris JC, Teshome M, Shah AR, Kauwe JS. Clifford DB, et al. Among authors: holtzman dm. Neurology. 2009 Dec 8;73(23):1982-7. doi: 10.1212/WNL.0b013e3181c5b445. Epub 2009 Nov 11. Neurology. 2009. PMID: 19907013 Free PMC article.

6

Relationship of dementia screening tests with biomarkers of Alzheimer's disease.

Galvin JE, Fagan AM, Holtzman DM, Mintun MA, Morris JC. Galvin JE, et al. Among authors: holtzman dm. Brain. 2010 Nov;133(11):3290-300. doi: 10.1093/brain/awq204. Epub 2010 Sep 7. Brain. 2010. PMID: 20823087 Free PMC article.

7

Comparison of analytical platforms for cerebrospinal fluid measures of β-amyloid 1-42, total tau, and p-tau181 for identifying Alzheimer disease amyloid plaque pathology.

Fagan AM, Shaw LM, Xiong C, Vanderstichele H, Mintun MA, Trojanowski JQ, Coart E, Morris JC, Holtzman DM. Fagan AM, et al. Among authors: holtzman dm. Arch Neurol. 2011 Sep;68(9):1137-44. doi: 10.1001/archneurol.2011.105. Epub 2011 May 9. Arch Neurol. 2011. PMID: 21555603 Free PMC article.

8

Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aβ amyloidosis.

Kim J, Eltorai AE, Jiang H, Liao F, Verghese PB, Kim J, Stewart FR, Basak JM, Holtzman DM. Kim J, et al. Among authors: holtzman dm. J Exp Med. 2012 Nov 19;209(12):2149-56. doi: 10.1084/jem.20121274. Epub 2012 Nov 5. J Exp Med. 2012. PMID: 23129750 Free PMC article.

9

SOD1 in cerebral spinal fluid as a pharmacodynamic marker for antisense oligonucleotide therapy.

Winer L, Srinivasan D, Chun S, Lacomis D, Jaffa M, Fagan A, Holtzman DM, Wancewicz E, Bennett CF, Bowser R, Cudkowicz M, Miller TM. Winer L, et al. Among authors: holtzman dm. JAMA Neurol. 2013 Feb;70(2):201-7. doi: 10.1001/jamaneurol.2013.593. JAMA Neurol. 2013. PMID: 23147550 Free PMC article.

10

Amyloid-β oligomerization in Alzheimer dementia versus high-pathology controls.

Esparza TJ, Zhao H, Cirrito JR, Cairns NJ, Bateman RJ, Holtzman DM, Brody DL. Esparza TJ, et al. Among authors: holtzman dm. Ann Neurol. 2013 Jan;73(1):104-19. doi: 10.1002/ana.23748. Epub 2012 Dec 7. Ann Neurol. 2013. PMID: 23225543 Free PMC article.

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