Lührmann R - Search Results

1

Identification of small molecule inhibitors of pre-mRNA splicing.

Pawellek A, McElroy S, Samatov T, Mitchell L, Woodland A, Ryder U, Gray D, Lührmann R, Lamond AI. Pawellek A, et al. Among authors: luhrmann r. J Biol Chem. 2014 Dec 12;289(50):34683-98. doi: 10.1074/jbc.M114.590976. Epub 2014 Oct 3. J Biol Chem. 2014. PMID: 25281741 Free PMC article.

2

Interaction of the human autoantigen p150 with splicing snRNPs.

Blencowe BJ, Carmo-Fonseca M, Behrens SE, Lührmann R, Lamond AI. Blencowe BJ, et al. Among authors: luhrmann r. J Cell Sci. 1993 Jul;105 ( Pt 3):685-97. doi: 10.1242/jcs.105.3.685. J Cell Sci. 1993. PMID: 8408296

3

Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing.

Makarova OV, Makarov EM, Liu S, Vornlocher HP, Lührmann R. Makarova OV, et al. Among authors: luhrmann r. EMBO J. 2002 Mar 1;21(5):1148-57. doi: 10.1093/emboj/21.5.1148. EMBO J. 2002. PMID: 11867543 Free PMC article.

4

Mutagenesis suggests several roles of Snu114p in pre-mRNA splicing.

Bartels C, Urlaub H, Luhrmann R, Fabrizio P. Bartels C, et al. Among authors: luhrmann r. J Biol Chem. 2003 Jul 25;278(30):28324-34. doi: 10.1074/jbc.M303043200. Epub 2003 May 7. J Biol Chem. 2003. PMID: 12736260 Free article.

5

Splicing of a rare class of introns by the U12-dependent spliceosome.

Will CL, Lührmann R. Will CL, et al. Among authors: luhrmann r. Biol Chem. 2005 Aug;386(8):713-24. doi: 10.1515/BC.2005.084. Biol Chem. 2005. PMID: 16201866 Review.

6

RNA structural requirements for the association of the spliceosomal hPrp31 protein with the U4 and U4atac small nuclear ribonucleoproteins.

Schultz A, Nottrott S, Hartmuth K, Lührmann R. Schultz A, et al. Among authors: luhrmann r. J Biol Chem. 2006 Sep 22;281(38):28278-86. doi: 10.1074/jbc.M603350200. Epub 2006 Jul 20. J Biol Chem. 2006. PMID: 16857676 Free article.

7

An unusual RNA recognition motif acts as a scaffold for multiple proteins in the pre-mRNA retention and splicing complex.

Trowitzsch S, Weber G, Lührmann R, Wahl MC. Trowitzsch S, et al. Among authors: luhrmann r. J Biol Chem. 2008 Nov 21;283(47):32317-27. doi: 10.1074/jbc.M804977200. Epub 2008 Sep 22. J Biol Chem. 2008. PMID: 18809678 Free article.

8

Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation.

Kuhn AN, van Santen MA, Schwienhorst A, Urlaub H, Lührmann R. Kuhn AN, et al. Among authors: luhrmann r. RNA. 2009 Jan;15(1):153-75. doi: 10.1261/rna.1332609. Epub 2008 Nov 24. RNA. 2009. PMID: 19029308 Free PMC article.

9

Exon definition complexes contain the tri-snRNP and can be directly converted into B-like precatalytic splicing complexes.

Schneider M, Will CL, Anokhina M, Tazi J, Urlaub H, Lührmann R. Schneider M, et al. Among authors: luhrmann r. Mol Cell. 2010 Apr 23;38(2):223-35. doi: 10.1016/j.molcel.2010.02.027. Mol Cell. 2010. PMID: 20417601 Free article.

10

Synthesis and characterization of pseudocantharidins, novel phosphatase modulators that promote the inclusion of exon 7 into the SMN (survival of motoneuron) pre-mRNA.

Zhang Z, Kelemen O, van Santen MA, Yelton SM, Wendlandt AE, Sviripa VM, Bollen M, Beullens M, Urlaub H, Lührmann R, Watt DS, Stamm S. Zhang Z, et al. Among authors: luhrmann r. J Biol Chem. 2011 Mar 25;286(12):10126-36. doi: 10.1074/jbc.M110.183970. Epub 2011 Jan 10. J Biol Chem. 2011. PMID: 21220421 Free PMC article.

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