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IGF2 preserves osteosarcoma cell survival by creating an autophagic state of dormancy that protects cells against chemotherapeutic stress.
Shimizu T, Sugihara E, Yamaguchi-Iwai S, Tamaki S, Koyama Y, Kamel W, Ueki A, Ishikawa T, Chiyoda T, Osuka S, Onishi N, Ikeda H, Kamei J, Matsuo K, Fukuchi Y, Nagai T, Toguchida J, Toyama Y, Muto A, Saya H. Shimizu T, et al. Among authors: toyama y. Cancer Res. 2014 Nov 15;74(22):6531-41. doi: 10.1158/0008-5472.CAN-14-0914. Epub 2014 Oct 1. Cancer Res. 2014. PMID: 25273088
IL-27 abrogates receptor activator of NF-kappa B ligand-mediated osteoclastogenesis of human granulocyte-macrophage colony-forming unit cells through STAT1-dependent inhibition of c-Fos.
Furukawa M, Takaishi H, Takito J, Yoda M, Sakai S, Hikata T, Hakozaki A, Uchikawa S, Matsumoto M, Chiba K, Kimura T, Okada Y, Matsuo K, Yoshida H, Toyama Y. Furukawa M, et al. Among authors: toyama y. J Immunol. 2009 Aug 15;183(4):2397-406. doi: 10.4049/jimmunol.0802091. Epub 2009 Jul 20. J Immunol. 2009. PMID: 19620301
Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury.
Tsuji O, Miura K, Okada Y, Fujiyoshi K, Mukaino M, Nagoshi N, Kitamura K, Kumagai G, Nishino M, Tomisato S, Higashi H, Nagai T, Katoh H, Kohda K, Matsuzaki Y, Yuzaki M, Ikeda E, Toyama Y, Nakamura M, Yamanaka S, Okano H. Tsuji O, et al. Among authors: toyama y. Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12704-9. doi: 10.1073/pnas.0910106107. Epub 2010 Jul 6. Proc Natl Acad Sci U S A. 2010. PMID: 20615974 Free PMC article.
Fibroblast growth factor-2 is an important factor that maintains cellular immaturity and contributes to aggressiveness of osteosarcoma.
Shimizu T, Ishikawa T, Iwai S, Ueki A, Sugihara E, Onishi N, Kuninaka S, Miyamoto T, Toyama Y, Ijiri H, Mori H, Matsuzaki Y, Yaguchi T, Nishio H, Kawakami Y, Ikeda Y, Saya H. Shimizu T, et al. Among authors: toyama y. Mol Cancer Res. 2012 Mar;10(3):454-68. doi: 10.1158/1541-7786.MCR-11-0347. Epub 2012 Jan 6. Mol Cancer Res. 2012. PMID: 22228819 Free article.
Up-regulation of Imp3 confers in vivo tumorigenicity on murine osteosarcoma cells.
Ueki A, Shimizu T, Masuda K, Yamaguchi SI, Ishikawa T, Sugihara E, Onishi N, Kuninaka S, Miyoshi K, Muto A, Toyama Y, Banno K, Aoki D, Saya H. Ueki A, et al. Among authors: toyama y. PLoS One. 2012;7(11):e50621. doi: 10.1371/journal.pone.0050621. Epub 2012 Nov 30. PLoS One. 2012. PMID: 23226335 Free PMC article.
1,145 results